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Critical Review of the Evidence in Regard to Supraesophageal Complications of Gastroesophageal Reflux Disease| Volume 108, ISSUE 4, SUPPLEMENT 1, 153-158, March 06, 2000

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Gastroesophageal reflux disease and asthma: the two are directly related

  • Joel E Richter
    Correspondence
    Requests for reprints should be addressed to Joel E. Richter, MD, Department of Gastroenterology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195
    Affiliations
    Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
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      In 1892, Osler
      • Osler W.B.
      first observed the association between worsening asthma and a distended stomach. However, it has only been in the past 2 decades that clinicians’ awareness of gastroesophageal reflux disease (GERD) as the cause of pulmonary diseases has increased. The majority of studies evaluating this association have focused on asthma, but other potential adult pulmonary manifestations of GERD include chronic bronchitis, aspiration pneumonia, bronchiectasis, and interstitial pulmonary fibrosis.
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