Abstract
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of MedicineReferences
- Melatonin, thymic serum factor, and cortisol levels in healthy subjects of different age and patients with skin melanoma.J Pineal Res. 1986; 3: 263-275
- Age- and sex-associated modification of plasma melatonin concentrations in man. Relationship to pathology, malignant or not, and autopsy findings.Acta Endocrinol. 1985; 108: 135-144
- Alterations in nocturnal serum melatonin levels in humans with growth and aging.J Clin Endocrinol Metab. 1988; 66: 648-652
- Hypothermic effect of melatonin and nocturnal core body temperature decline are reduced in aged women.J Appl Physiol. 1995; 78: 314-317
- Variations of melatonin incretion in elderly patients affected by cerebral deterioration.Arch Gerontol Geriatr. 1991; S2: 123-126
- A chronobiological study of melatonin and cortisol secretion in depressed subjects.Biol Psychiatry. 1984; 19: 1215-1228
- Chrono-neuroendocrine markers of the aging brain.Aging Clin Exp Res. 1996; 8: 320-327
- Differential changes in amplitude with aging in blind persons.Soc Res Biol Rhythms. 1996; 5: 131
- Relationship between melatonin rhythms and visual loss in the blind.J Clin Endocrinol Metab. 1997; 82: 3763-3770
- Circadian secretion of melatonin and thyrotropin in hospitalized aged patients.Aging Clin Exp Res. 1993; 5: 39-46
- Differential pattern of the circadian rhythm of serum melatonin in young and elderly healthy subjects.Biol Signals. 1997; 6: 301-306
- Patterns of plasma melatonin with ageing and mental condition.Acta Endocrinol. 1984; 106: 145-151
- Seasonal changes in the levels of antidiuretic hormone and melatonin in the elderly.J Pineal Res. 1995; 18: 154-158
- Age, alcoholism and depression are associated with low levels of urinary melatonin.J Psychiatr Neurosci. 1992; 17: 215-224
- Factors influencing urinary 6-sulphatoxymelatonin, a major melatonin metabolite, in normal human subjects.Clin Endocrinol. 1990; 33: 435-444
- Melatonin in human cerebrospinal fluid in daytime; its origin and variation with age.Life Sci. 1979; 25: 929-936
- Chrono-neuroendocrinological aspects of physiological aging and senile dementia.Chronobiologia. 1994; 21: 121-126
- Age-dependent reduction in serum melatonin concentrations in healthy human subjects.J Clin Endocrinol Metab. 1982; 55: 27-29
- Attenuation of the circadian rhythms of core body temperature and melatonin with aging in women.Endocrine Society Abstracts. 1992; 74: 251
- Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging.Chronobiol Int. 1997; 14: 385-396
- Circadian rhythm of plasma melatonin in endogenous depression.Prog Neuro-Psychopharmacol Biol Psychiat. 1984; 8: 715-718
- Plasma melatonin—an index of brain aging in humans?.Biol Psychiatry. 1986; 21: 141-150
- Age and plasma levels of melatonin and N-acetylserotonin in human beings.Neurosci Lett. 1984; 16: S25
- Human melatonin production decreases with age.J Pineal Res. 1986; 3: 379-388
- Circadian rhythms of melatonin and cortisol in aging.Biol Psychiatry. 1989; 25: 305-319
- Melatonin secretion and age.Biol Psychiatry. 1989; 25: 365-367
- Some aspects of the circadian time structure in the elderly.Gerontology. 1982; 28: 53-67
- Age-, and mental health-related circadian rhythms of plasma levels of melatonin, prolactin, luteinizing hormone and follicle-stimulating hormone in man.J Endocrinol. 1981; 91: 467-475
- Neuroendocrine rhythms and sleep in aging men.Am J Physiol. 1991; 260: E651-E661
- Constant pineal output and increasing body mass account for declining melatonin levels during human growth and sexual maturation.J Pineal Res. 1988; 5: 71-85
- Melatonin.Ann Med. 1998; 30: 81-87
- Neuroendocrine correlates of the aging brain in humans.Neuroendocrinology. 1995; 61: 464-470
- Sleep disorders and melatonin rhythms in elderly people.BMJ. 1994; 309: 167
- Urinary 6-sulphatoxymelatonin excretion in breast cancer patients and control subjects.in: Fraschini F. Reiter R.J. Role of Melatonin and Pineal Peptides in Neuroimmunomodulation. Plenum Press, New York1991: 301-305
- Circadian rhythm of plasma melatonin and cortisol in endogenous depression.in: Brown G.M. Wainwright S.D. The Pineal Gland Endocrine Aspects. Pergamon Press, New York1985: 339-345
- Melatonin in human serum.in: Birau N. Schloot W. Melatonin Current Status and Perspectives. Pergamon Press, New York1981: 297-326
- Reduced nocturnal melatonin secretion in chronic schizophrenia.Clin Endocrinol. 1982; 17: 181-187
- Circadian Physiology and the Plasma Melatonin Rhythm in Humans [thesis]. Harvard University Medical School, Boston, MA1995
- Posture influences melatonin concentrations in plasma and saliva in humans.Neurosci Lett. 1994; 167: 191-194
- Posture.in: Touitou Y. Arendt J. Pévet P. Melatonin and the Pineal Gland From Basic Science to Clinical Application. Elsevier Science Publishers, New York1993: 387-390
- Adaptation to abrupt time shifts of the oscillator[s] controlling human circadian rhythms.J Physiol (Lond). 1978; 285: 455-470
- Bright light induction of strong (type 0) resetting of the human circadian pacemaker.Science. 1989; 244: 1328-1333
- Exposure to bright light and darkness to treat physiologic maladaptation to night work.NEJM. 1990; 322: 1253-1259
- The role of melatonin and circadian phase in age-related sleep-maintenance insomnia.Sleep. 1998; 21: 52-68
Collins SA. Systeme of Anatomy. London: Newcomb, 1685:1020–1021.
Kitay JI, Altschule MD. The Pineal Gland: A Review of the Physiologic Literature. Cambridge: Harvard University Press, 1954:77–78.
- Does a centralized clock for aging exist?.Gerontology. 1990; 36: 314-322
- The pineal gland and melatonin in relation to aging.Exp Gerontol. 1995; 30: 199-212
- Timekeeping in genetically programmed aging.Exp Gerontol. 1993; 28: 109-118
- Nonsteroidal anti-inflammatory drugs alter body temperature and suppress melatonin in humans.Physiol Behav. 1996; 59: 133-139
- Human melatonin suppression by light is intensity dependent.J Pineal Res. 1989; 6: 149-156
- The relationship between urinary 6-sulphatoxymelatonin rhythm and insomnia in old age.Adv Pineal Res. 1994; 8: 433-438
- The Melatonin Miracle. Simon and Shuster, New York1995
- Structural characterization of contaminants found in commercial preparations of melatonin.Chem Res Toxicol. 1998; 11: 234-240
Borbély AA. Commentary on the articles by Arendt, Weaver, Mahle et al., and Guardiola-Lemat̂re. J Biol Rhythms 1997;12:707–708.
- Guidelines for prescribing melatonin.Ann Med. 1998; 30: 122-130
Article Info
Publication History
Footnotes
☆Supported in part by grants from the National Institute on Aging (P01-AG-09975; R01-AG06072), the National Institute of Mental Health (R01-MH-45130), a General Clinical Research Center grant from the National Center for Research Resources (M01-RR02635), and the National Aeronautics and Space Administration (NAG 5–3952; NAG W-4033).