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Gastrointestinal side effects of nonsteroidal anti-inflammatory drugs

  • Byron Cryer
    Correspondence
    Requests for reprints should be addressed to Byron L. Cryer, MD, or Michael B. Kimmey, MD, University of Texas, Southwestern Medical School and Dallas VA Medical Center (111B1), 4500 South Lancaster Road, Dallas, Texas 75216
    Affiliations
    Division of Gastroenterology, University of Texas Southwestern Medical School, Dallas, Texas, USA
    Search for articles by this author
  • Michael B. Kimmey
    Affiliations
    University of Washington Medical School, Seattle, Washington, USA
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      Abstract

      The gastrointestinal (GI) tract is the most common location for side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs may cause problems in any part of the GI tract, from the esophagus to the rectum. The severity of these side effects ranges from nuisance symptoms such as dyspepsia to life-threatening ulcer complications. The diagnosis, treatment, and prevention of the various GI side effects of these commonly prescribed drugs are reviewed in this article.
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