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The Evolution of Cardiovascular Ultrasound: A Review of Cardiac Point-of-Care Ultrasound (POCUS) Across Specialties

Open AccessPublished:March 06, 2023DOI:https://doi.org/10.1016/j.amjmed.2023.02.020

      Abstract

      The use of cardiac point-of-care ultrasound (POCUS) is now widespread in clinics, emergency departments, and all areas of the hospital. Users include medical trainees, advanced practice practitioners, and attending physicians in many specialties and sub-specialties. Opportunities to learn cardiac POCUS and requirements for training vary across specialties, as does the scope of the cardiac POCUS examination. In this review, we describe both a brief history of how cardiac POCUS emerged from echocardiography and the state of the art across a variety of medical fields.

      Keywords

      Clinical Significance
      • Cardiac POCUS is in widespread use by many different specialists.
      • Cardiac POCUS is used in a range of settings from home-based care, to clinics, to all areas of the hospital.
      • Cardiac POCUS training and core applications vary among specialties.

      Introduction

      In 1963, a cardiologist borrowed a neurologist's ultrasound probe and placed it on the chest of a patient to determine if he could detect a pericardial effusion.
      • Feigenbaum H
      Evolution of echocardiography.
      At this fundamental level, the application of a probe at the point-of-care was simply cardiovascular ultrasound. The term “echocardiography” developed to encompass various aspects of a burgeoning field including training, protocolization, quality control, and technologic development.
      • Feigenbaum H
      Evolution of echocardiography.
      As cardiovascular ultrasound became invaluable to the diagnostic process, the North American response to high-volume demand was separation of skills in acquisition and interpretation to create an efficient delivery service: the echocardiography laboratory. To maintain quality, guidelines and standards developed further. These, along with the cost of an ever-sophisticated machine, created barriers to entering the practice of echocardiography. Thus, application of cardiovascular ultrasound ended up in the domain of specialists following a practice competency pathway. However, the practice of cardiovascular ultrasound continues to evolve, and perhaps it may now be seen as a ‘devolution’ from the structured echocardiography lab, back to its origins, and into the hands of nonconventional users. This review summarizes the current state of cardiac point-of-care ultrasound (POCUS) incorporated by various specialties.

      Choosing the Term "Cardiac POCUS"

      In the early 2000s, there was some obfuscation of whether bedside ultrasound scans should be considered echocardiograms. There was an outpouring of terms, including bedside ultrasound, mini-echo, portable echo, handheld ultrasound, pocket echo, and focused ultrasound. In an early report by members of the American Society of Echocardiography, the term POCUS was suggested to distinguish bedside scans from echocardiography to preserve the standards, training, and reporting structure innovated by the formal services of echocardiography labs.
      • Johri AM
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      • Newbigging J
      • et al.
      Cardiac point-of-care ultrasound: state-of-the-art in medical school education.
      ,
      • Via G
      • Hussain A
      • Wells M
      • et al.
      International evidence-based recommendations for focused cardiac ultrasound.
      In this classification, both echocardiogram and cardiac POCUS may be viewed as a subset of the general term cardiovascular ultrasound. The term cardiac POCUS gained further global acceptance during the COVID-19 pandemic to best describe provider-led, bedside scanning, reducing exposure to contagion for other personnel and facilities, and is now the principal terminology utilized for this connotation.
      • Johri AM
      • Galen B
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      ASE statement on point-of-care ultrasound during the 2019 novel coronavirus pandemic.
      Recognition that POCUS users are not performing a complete echocardiogram reduces barriers to entry to cardiovascular ultrasound, freeing POCUS users to come from differing training backgrounds. Distinguishing “cardiac POCUS” from echocardiography also frees it from the advanced tools recommended to comprise a formal echocardiogram including 3D, contrast, and strain analysis. This term is also consistent with, and useful for, descriptions of other noncardiac types of POCUS, such as chest POCUS or renal POCUS.

      The Definition of Cardiac POCUS: Limitations and Freedoms

      Cardiac POCUS is the application of cardiovascular ultrasound, to assess the heart and its vessels by the medical provider at the bedside, to answer an immediate question. Cardiac POCUS is limited in scope, defined by the skill set of the operator, and the indication particular to their specialty area. Thus, there are multiple secondary definitions of cardiac POCUS, varying by specialty. However, a common feature of cardiac POCUS across specialties is its distinction from an echocardiogram. Whereas an echocardiogram is a formal, requisition-based referral service that always 1) is acquired by a credentialed sonographer following a defined protocol, 2) is interpreted by a trained physician, 3) provides a structured report, 4) is archived, and 5) is usually conducted through a formal testing facility, cardiac POCUS does not require any of these 5 components. POCUS has an inherent freedom from the requirements of a formal echocardiogram, although it remains limited in scope. The degree of freedom varies by resource setting, institutional requirements, and policy, and as scope evolves among specialties.

      Cardiac POCUS Across Specialties of Clinical Practice

      Emergency Medicine

      Emergency medicine physicians were among the first specialists to perform limited bedside cardiac ultrasound with the primary goals of identifying life-threatening conditions such as cardiac tamponade or significant reduction in left ventricular function. Cardiac POCUS grew out of a larger effort to facilitate rapid bedside diagnoses of many emergency conditions using ultrasound, such as aortic aneurysm, abdominal bleeding in the setting of trauma, and ectopic pregnancy. Ultrasound education is now widespread in North American emergency medicine training programs, and the scope of bedside cardiac assessment includes visual assessment of ejection fraction and pericardial effusion, but may also extend to basic quantitative left ventricular function, right ventricular strain, and simple measures of diastolic dysfunction. Cardiac POCUS in the emergency setting continues to focus on assessments that reduce the differential diagnosis for a particular patient encounter, guide further care, and facilitate the diagnosis of emergent conditions.
      Instruction in cardiac POCUS for emergency medicine trainees has been endorsed by the Royal College of Physicians and Surgeons of Canada and the American Board of Emergency Medicine.
      • Counselman FL
      • Borenstein MA
      • Chisholm CD
      • et al.
      The 2013 model of the clinical practice of emergency medicine.
      ,

      Royal College of Physicians and Surgeons of Canada. Emergency medicine competencies (2018 v 1.0). Available at:https://www.royalcollege.ca/rcsite/documents/ibd/emergency-medecine-competencies-e.pdf. Accessed November 10, 2022.

      The Canadian Academy of Emergency Physicians, the American College of Emergency Physicians, and the American Academy of Emergency Medicine all recognize cardiac POCUS as a core competency for emergency medicine.
      • Olszynski P
      • Kim DJ
      • Chenkin J
      • Rang L
      The CAEP emergency ultrasound curriculum – objectives and recommendations for implementation in postgraduate training: executive summary.
      Ultrasound guidelines: emergency, point-of-care and clinical ultrasound guidelines in medicine.

      American Academy of Emergency Medicine (AAEM). Performance of emergency screening ultrasound examinations. Published February 1, 1999. Available at:https://www.aaem.org/resources/statements/position/performance-of-emergency-screening-ultrasound-examinations. Accessed November 10, 2022.

      Ultrasound training for residents is integrated into the specialty training curriculum, while physicians in practice typically complete a minimum of 16 hours of didactic instruction (including hands-on experience) followed by 150 supervised scans across a variety of core study types.
      Ultrasound guidelines: emergency, point-of-care and clinical ultrasound guidelines in medicine.
      ,
      • Lewis D
      • Rang L
      • Kim D
      • et al.
      Recommendations for the use of point-of-care ultrasound (POCUS) by emergency physicians in Canada.
      In the last 20 years a sub-specialist class of emergency medicine physicians has developed, who—either by virtue of prior practice or additional fellowship training—have achieved additional competencies that include spectral Doppler modalities, regional wall motion assessment, and (in some cases) transesophageal qualifications. There is no recognized certification in ultrasound for emergency physicians beyond completion of residency training or documentation of completion of a practice-based training pathway. US ultrasound fellowship graduates may pursue a Focused Practice Designation in Advanced Emergency Ultrasound from the American Board of Emergency Medicine by completing a written examination.

      American Board of Emergency Medicine - ABEM. Advanced emergency medicine ultrasound (AEMUS) eligibility criteria for focused practice designation. 2021. Available at:https://www.abem.org/public/docs/default-source/default-document-library/eligibility_criteria_aemus.pdf?sfvrsn=84f4cff4_22. Accessed November 10, 2022.

      Canadian physicians can optionally complete certifications through the Canadian POCUS Society. To conduct cardiac POCUS examinations, a minimal degree of training has been defined, although there is no recognized certification beyond residency that is required to practice (Table
      • Koratala A
      • Olaoye OA
      • Bhasin-Chhabra B
      • Kazory A
      A blueprint for an integrated point-of-care ultrasound curriculum for nephrology trainees.
      • LoPresti CM
      • Jensen TP
      • Dversdal RK
      • Astiz DJ
      Point-of-care ultrasound for internal medicine residency training: a position statement from the alliance of academic internal medicine.
      • Soni NJ
      • Schnobrich D
      • Mathews BK
      • et al.
      Point-of-care ultrasound for hospitalists: a position statement of the Society of Hospital Medicine.
      • Reaume M
      • Siuba M
      • Wagner M
      • Woodwyk A
      • Melgar TA
      Prevalence and scope of point-of-care ultrasound education in internal medicine, pediatric, and medicine-pediatric residency programs in the United States.

      Pustavoitau A, Blaivas M, Brown SM, et al. Recommendations for achieving and maintaining competence and credentialing in critical care ultrasound with focused cardiac ultrasound and advanced critical care echocardiography. Available at:https://journals.lww.com/ccmjournal/Documents/Critical%20Care%20Ultrasound.pdf. Accessed June 28, 2022.

      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      • Mahmood F
      • Matyal R
      • Skubas N
      • et al.
      Perioperative ultrasound training in anesthesiology: a call to action.
      • Meineri M
      • Arellano R
      • Bryson G
      • et al.
      Canadian recommendations for training and performance in basic perioperative point-of-care ultrasound: recommendations from a consensus of Canadian anesthesiology academic centres.
      • Arntfield RT
      • Millington SJ
      • Ainsworth CD
      • et al.
      Canadian recommendations for critical care ultrasound training and competency.
      • Haskins SC
      • Bronshteyn Y
      • Perlas A
      • et al.
      American Society of Regional Anesthesia and Pain Medicine expert panel recommendations on point-of-care ultrasound education and training for regional anesthesiologists and pain physicians-part I: clinical indications.
      • Fagley RE
      • Haney MF
      • Beraud AS
      • et al.
      Critical care basic ultrasound learning goals for American anesthesiology critical care trainees: recommendations from an expert group.
      • Baribeau Y
      • Sharkey A
      • Chaudhary O
      • et al.
      Handheld point-of-care ultrasound probes: the new generation of POCUS.
      • Kirkpatrick JN
      • Grimm R
      • Johri AM
      • et al.
      Recommendations for echocardiography laboratories participating in cardiac point of care cardiac ultrasound (POCUS) and critical care echocardiography training: report from the American Society of Echocardiography.
      • Spencer KT
      • Kimura BJ
      • Korcarz CE
      • Pellikka PA
      • Rahko PS
      • Siegel RJ
      Focused cardiac ultrasound: recommendations from the American Society of Echocardiography.
      • Mayo PH
      • Beaulieu Y
      • Doelken P
      • et al.
      American College of Chest Physicians/La Société de Réanimation de Langue Française statement on competence in critical care ultrasonography.
      • Price S
      • Via G
      • Sloth E
      • et al.
      Echocardiography practice, training and accreditation in the intensive care: document for the World Interactive Network Focused on Critical Ultrasound (WINFOCUS).
      • Guevarra K
      • Greenstein Y
      Ultrasonography in the critical care unit.
      • Labovitz AJ
      • Noble VE
      • Bierig M
      • et al.
      Focused cardiac ultrasound in the emergent setting: a consensus statement of the American society of Echocardiography and American College of Emergency Physicians.
      • Henneberry RJ
      • Hanson A
      • Healey A
      • et al.
      Use of point of care sonography by emergency physicians.
      • Whitson MR
      • Mayo PH
      Ultrasonography in the emergency department.

      American Association of Family Physicians (AAFP). Recommended curriculum guidelines for family medicine residents: point-of-care ultrasound. 2021. Available at:https://www.aafp.org/dam/AAFP/documents/medical_education_residency/program_directors/Reprint290D_POCUS.pdf. Accessed September 24, 2022.

      • Ma IWY
      • Hussain A
      • Wagner M
      • et al.
      Canadian Internal Medicine Ultrasound (CIMUS) expert consensus statement on the use of lung ultrasound for the assessment of medical inpatients with known or suspected coronavirus disease 2019.
      • Torres-Macho J
      • Aro T
      • Bruckner I
      • et al.
      Point-of-care ultrasound in internal medicine: a position paper by the ultrasound working group of the European Federation of Internal Medicine.
      • Jain V
      • O'Quinn C
      • Van den Hof M
      Guideline no. 421: point of care ultrasound in obstetrics and gynaecology.
      • Lammers S
      • Dolin CD
      • Baston C
      A call for development of point-of-care ultrasound training recommendations in obstetrics and gynecology residency.
      • Marin JR
      • Lewiss RE
      Point-of-care ultrasonography by pediatric emergency physicians. Policy statement.
      ).
      TableCardiac POCUS Across Medical Specialties
      SpecialtyRecommending AgenciesAvailable TrainingCore Cardiac Applications of POCUS
      AnesthesiologyASRA,
      • Haskins SC
      • Bronshteyn Y
      • Perlas A
      • et al.
      American Society of Regional Anesthesia and Pain Medicine expert panel recommendations on point-of-care ultrasound education and training for regional anesthesiologists and pain physicians-part I: clinical indications.
      CAS,
      • Meineri M
      • Arellano R
      • Bryson G
      • et al.
      Canadian recommendations for training and performance in basic perioperative point-of-care ultrasound: recommendations from a consensus of Canadian anesthesiology academic centres.
      SOCCA
      • Fagley RE
      • Haney MF
      • Beraud AS
      • et al.
      Critical care basic ultrasound learning goals for American anesthesiology critical care trainees: recommendations from an expert group.
      Not mandated in most residency programs.
      • Baribeau Y
      • Sharkey A
      • Chaudhary O
      • et al.
      Handheld point-of-care ultrasound probes: the new generation of POCUS.
      External training opportunities available.
      Hemodynamic evaluation, volume status, myocardial ischemia, ventricular size and function, valvular abnormalities, hypertrophic cardiomyopathy, evaluation of pericardium (effusion, tamponade, guidance in pericardiocentesis), detection of pacing capture, cardiac arrest
      • Mahmood F
      • Matyal R
      • Skubas N
      • et al.
      Perioperative ultrasound training in anesthesiology: a call to action.
      ,
      • Meineri M
      • Arellano R
      • Bryson G
      • et al.
      Canadian recommendations for training and performance in basic perioperative point-of-care ultrasound: recommendations from a consensus of Canadian anesthesiology academic centres.
      CardiologyASE
      • Kirkpatrick JN
      • Grimm R
      • Johri AM
      • et al.
      Recommendations for echocardiography laboratories participating in cardiac point of care cardiac ultrasound (POCUS) and critical care echocardiography training: report from the American Society of Echocardiography.
      ,
      • Spencer KT
      • Kimura BJ
      • Korcarz CE
      • Pellikka PA
      • Rahko PS
      • Siegel RJ
      Focused cardiac ultrasound: recommendations from the American Society of Echocardiography.
      Training mandated in majority of internal medicine/cardiology residency programs. Additional fellowship training in formal echocardiography is common.Ventricular size and function, elevated left heart filling pressures, valvular abnormalities, left ventricular hypertrophy, hypertrophic cardiomyopathy, aortic aneurysm, pericardial effusion, cardiac arrest
      Critical careACCP,
      • Mayo PH
      • Beaulieu Y
      • Doelken P
      • et al.
      American College of Chest Physicians/La Société de Réanimation de Langue Française statement on competence in critical care ultrasonography.
      CCCS,
      • Arntfield RT
      • Millington SJ
      • Ainsworth CD
      • et al.
      Canadian recommendations for critical care ultrasound training and competency.
      SCCM,

      Pustavoitau A, Blaivas M, Brown SM, et al. Recommendations for achieving and maintaining competence and credentialing in critical care ultrasound with focused cardiac ultrasound and advanced critical care echocardiography. Available at:https://journals.lww.com/ccmjournal/Documents/Critical%20Care%20Ultrasound.pdf. Accessed June 28, 2022.

      WINFOCUS
      • Price S
      • Via G
      • Sloth E
      • et al.
      Echocardiography practice, training and accreditation in the intensive care: document for the World Interactive Network Focused on Critical Ultrasound (WINFOCUS).
      Not mandated in all fellowship programs.
      • Guevarra K
      • Greenstein Y
      Ultrasonography in the critical care unit.
      External training opportunities available.
      Shock, ventricular size and function, wall motion abnormalities, valvular abnormalities, TEE in cardiac arrest, management of mechanical/extracorporeal support
      Emergency medicineACEP,
      • Labovitz AJ
      • Noble VE
      • Bierig M
      • et al.
      Focused cardiac ultrasound in the emergent setting: a consensus statement of the American society of Echocardiography and American College of Emergency Physicians.
      CAEP
      • Henneberry RJ
      • Hanson A
      • Healey A
      • et al.
      Use of point of care sonography by emergency physicians.
      Training mandated in majority of residency and fellowships.
      • Whitson MR
      • Mayo PH
      Ultrasonography in the emergency department.


      External training opportunities available.
      Ventricular size and function, identifying pericardial effusion, volume status, guiding pericardiocentesis, confirmation of transvenous pacing wire placement, aortic aneurysm
      Family medicineAAFP

      American Association of Family Physicians (AAFP). Recommended curriculum guidelines for family medicine residents: point-of-care ultrasound. 2021. Available at:https://www.aafp.org/dam/AAFP/documents/medical_education_residency/program_directors/Reprint290D_POCUS.pdf. Accessed September 24, 2022.

      Not mandated in most residency programs. AAFP has published recommended curriculum guidelines.Ventricular size and function, pericardial effusion, valvular function, volume status
      Internal medicineAAIM,
      • LoPresti CM
      • Jensen TP
      • Dversdal RK
      • Astiz DJ
      Point-of-care ultrasound for internal medicine residency training: a position statement from the alliance of academic internal medicine.
      CIMUS,
      • Ma IWY
      • Hussain A
      • Wagner M
      • et al.
      Canadian Internal Medicine Ultrasound (CIMUS) expert consensus statement on the use of lung ultrasound for the assessment of medical inpatients with known or suspected coronavirus disease 2019.
      EFIM,
      • Torres-Macho J
      • Aro T
      • Bruckner I
      • et al.
      Point-of-care ultrasound in internal medicine: a position paper by the ultrasound working group of the European Federation of Internal Medicine.
      SHM
      • Soni NJ
      • Schnobrich D
      • Mathews BK
      • et al.
      Point-of-care ultrasound for hospitalists: a position statement of the Society of Hospital Medicine.
      Training mandated in majority of residency programs. External training opportunities available.Ventricular size and function, pericardial effusion, atrial size, valvular function, volume status, aortic aneurysm
      NephrologyNo published POCUS guidelines/

      recommendations
      Fellowship curriculums have been proposed.
      • Koratala A
      • Olaoye OA
      • Bhasin-Chhabra B
      • Kazory A
      A blueprint for an integrated point-of-care ultrasound curriculum for nephrology trainees.
      Ventricular size and function, pericardial effusion, volume status, cardiac output
      Obstetrics-GynecologySOGC
      • Jain V
      • O'Quinn C
      • Van den Hof M
      Guideline no. 421: point of care ultrasound in obstetrics and gynaecology.
      Not mandated in residency or fellowship programs.
      • Lammers S
      • Dolin CD
      • Baston C
      A call for development of point-of-care ultrasound training recommendations in obstetrics and gynecology residency.
      Bedside assessment for fetal cardiac activity, Doppler assessment of fetal circulation
      Pediatrics/NeonatologyESPNIC,
      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      AAP
      • Marin JR
      • Lewiss RE
      Point-of-care ultrasonography by pediatric emergency physicians. Policy statement.
      Not mandated in most residency programs.
      • Reaume M
      • Siuba M
      • Wagner M
      • Woodwyk A
      • Melgar TA
      Prevalence and scope of point-of-care ultrasound education in internal medicine, pediatric, and medicine-pediatric residency programs in the United States.
      Mandated in pediatric emergency medicine fellowships.
      • Marin JR
      • Lewiss RE
      Point-of-care ultrasonography by pediatric emergency physicians. Policy statement.
      Tamponade and pericardial effusion, ventricular size and function, assessment of umbilical venous catheters and central lines, assessment cardiac filling and volume status
      AAFP = American Association of Family Physicians; AAIM = Alliance for Academic Internal Medicine; AAP = American Academy of Pediatrics; ACCP = American College of Chest Physicians; ACEP = American College of Emergency Physicians; ASE = American Society of Echocardiography; ASRA = American Society of Regional Anesthesia; CAEP = Canadian Association of Emergency Physicians; CAS = Canadian Anesthesiologists’ Society; CCCS = Canadian Critical Care Society; CIMUS = Canadian Internal Medicine Ultrasound group; eFAST = extended focused assessment with sonography for trauma; EFIM = European Federation of Internal Medicine; ESPNIC = European Society of Paediatric and Neonatal Intensive Care; FAST = focused assessment with sonography for trauma; POCUS = point-of-care ultrasound; SCCM = Society of Critical Care Medicine; SHM = Society of Hospital Medicine; SOCCA = Society of Critical Care Anesthesiologists; SOGC = Society of Obstetrician and Gynaecologists of Canada; SOHM = Society of Hospital Medicine; TEE = transesophageal echocardiogram; WINFOCUS = World Interactive Network Focused on Critical Ultrasound.

      Family Medicine

      Cardiac POCUS is used in all settings where family medicine clinicians practice, both outpatient and inpatient settings: urgent care, home-based care, and hospital wards. For most family medicine physicians, POCUS has been adopted as an extension of the cardiovascular physical examination and clinical assessment.
      • Lee L
      • DeCara JM
      Point-of-care ultrasound.
      The American Academy of Family Physicians published the Recommended Curriculum Guidelines for family medicine residents in 2018,

      American Academy of Family Physicians (AAFP). Recommended curriculum guidelines for family medicine residents: point-of-care ultrasound. Available at:https://www.aafp.org/dam/AAFP/documents/medical_education_residency/program_directors/Reprint290D_POCUS.pdf. Accessed November 10, 2022.

      and cardiac POCUS was recommended as one of the basic core applications of POCUS. Basic skills in cardiac POCUS are used for detection of pericardial effusion, assessment of global left ventricular contractility, assessment of right ventricular size, and measurement of inferior vena cava as part of the volume status examination.

      American Academy of Family Physicians (AAFP). Recommended curriculum guidelines for family medicine residents: point-of-care ultrasound. Available at:https://www.aafp.org/dam/AAFP/documents/medical_education_residency/program_directors/Reprint290D_POCUS.pdf. Accessed November 10, 2022.

      Advanced Primary Care Ultrasound Fellowship programs provide training for basic skills as well as advanced skills like calculation of ejection fraction, regional wall motion abnormalities, diastolic dysfunction, left ventricular hypertrophy, and valvular abnormalities including mitral/aortic regurgitation and stenosis. The use of cardiac POCUS is widely recommended by the American Academy of Family Physicians, American College of Physicians, and Society of Hospital Medicine
      • Qaseem A
      • Etxeandia-Ikobaltzeta I
      • Mustafa RA
      • Kansagara D
      • Fitterman N
      • Wilt TJ
      Appropriate use of point-of-care ultrasonography in patients with acute dyspnea in emergency department or inpatient settings: a clinical guideline from the american college of physicians.
      (Table).
      An important application of cardiac POCUS for family medicine physicians is in remote or resource-limited settings. Cardiac POCUS may be the only option for underserved settings where a high-end echocardiography machine may be cost-prohibitive and where POCUS availability may help reduce health care disparities.
      • Kirkpatrick JN
      • Davis A
      • DeCara JM
      • et al.
      Hand-carried cardiac ultrasound as a tool to screen for important cardiovascular disease in an underserved minority health care clinic.

      Internal Medicine

      Cardiac POCUS use within internal medicine is now both prevalent and rapidly increasing. Subspecialists of internal medicine in critical care medicine were among the earliest adopters of cardiac POCUS, following the lead of their emergency medicine colleagues for urgent evaluation of acutely decompensating patients.
      • Frankel HL
      • Kirkpatrick AW
      • Elbarbary M
      • et al.
      Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients-part i: general ultrasonography.
      ,
      • Levitov A
      • Frankel HL
      • Blaivas M
      • et al.
      Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients-part ii: cardiac ultrasonography.
      Yet over the last decade, POCUS has spread broadly throughout internal medicine, being used by hospitalists, primary care providers, and many subspecialists.
      • Koratala A
      • Olaoye OA
      • Bhasin-Chhabra B
      • Kazory A
      A blueprint for an integrated point-of-care ultrasound curriculum for nephrology trainees.
      ,
      • Matsuki-Muramoto Y
      • Ogasawara M
      • Kawamoto T
      • Yamaji K
      • Tamura N
      Picture superiority effect as one of the potential advantages of musculoskeletal ultrasound complementation for verbal explanation.
      ,
      • Pinto J
      • Azevedo R
      • Pereira E
      • Caldeira A
      Ultrasonography in gastroenterology: the need for training.
      POCUS, including cardiac applications, is now endorsed by some of the largest internal medicine professional organizations, including the Academic Alliance for Internal Medicine, the American College of Physicians, the Society of Hospital Medicine, and the Society of Critical Care Medicine.
      • LoPresti CM
      • Jensen TP
      • Dversdal RK
      • Astiz DJ
      Point-of-care ultrasound for internal medicine residency training: a position statement from the alliance of academic internal medicine.
      ,
      • Soni NJ
      • Schnobrich D
      • Mathews BK
      • et al.
      Point-of-care ultrasound for hospitalists: a position statement of the Society of Hospital Medicine.
      ,
      • Frankel HL
      • Kirkpatrick AW
      • Elbarbary M
      • et al.
      Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients-part i: general ultrasonography.
      ,
      • Levitov A
      • Frankel HL
      • Blaivas M
      • et al.
      Guidelines for the appropriate use of bedside general and cardiac ultrasonography in the evaluation of critically ill patients-part ii: cardiac ultrasonography.
      ,

      American College of Physicians. ACP statement in support of point-of-care ultrasound in internal medicine. ACP point of care ultrasound (POCUS) for internal medicine. Available at:https://www.acponline.org/meetings-courses/focused-topics/point-of-care-ultrasound-pocus-for-internal-medicine/acp-statement-in-support-of-point-of-care-ultrasound-in-internal-medicine. Accessed November 10, 2022.

      Additionally, many of those societies who haven't issued a formal statement have shown support through building educational tools and courses.

      Society of General Internal Medicine (SGIM). SGIM offerings. Published 2022. Available at:https://www.sgim.org/communities/clinical-practice/improving-care/point-of-care-ultrasound-pocus#. Accessed November 10, 2022.

      Nearly all endorsements and available trainings include cardiac POCUS as a core component (Table).
      Despite the increase in use and organizational support, at present there are no formal internal medicine residency training requirements set by the American Board of Internal Medicine. Yet the landscape of POCUS training is changing rapidly; with 25% of internal medicine residency programs reported formal training in POCUS in 2012, increasing to 61% in 2020.
      • Reaume M
      • Siuba M
      • Wagner M
      • Woodwyk A
      • Melgar TA
      Prevalence and scope of point-of-care ultrasound education in internal medicine, pediatric, and medicine-pediatric residency programs in the United States.
      ,
      • Schnobrich DJ
      • Gladding S
      • Olson APJ
      • Duran-Nelson A
      Point-of-care ultrasound in internal medicine: a national survey of educational leadership.
      ,
      • LoPresti CM
      • Schnobrich D
      • Novak W
      • et al.
      Current point of care ultrasound use and training among internal medicine residency programs from the 2020 APDIM program director's survey.
      Additionally, there are now several internal medicine POCUS fellowships available for advanced POCUS training after residency, although these remain uncertified by the Accreditation Council for Graduate Medical Education at this time.

      Pustavoitau A, Blaivas M, Brown SM, et al. Recommendations for achieving and maintaining competence and credentialing in critical care ultrasound with focused cardiac ultrasound and advanced critical care echocardiography. Available at:https://journals.lww.com/ccmjournal/Documents/Critical%20Care%20Ultrasound.pdf. Accessed June 28, 2022.

      ,

      Weill Cornell Medicine. Hospital Medicine Clinical Point of Care Ultrasound Fellowship. Published 2022. Available at:https://medicine.weill.cornell.edu/divisions-programs/general-internal-medicine/education/residents-and-fellows/hospital-medicine. Accessed November 10, 2022.

      The scope of cardiac POCUS use in internal medicine depends on both the environment where it is practiced and the skill of the practitioner who uses it. Yet, generally recognized core examinations largely mirror those of emergency medicine, including qualitative assessment of left ventricular systolic function, identification of pericardial effusions, relative chamber size, and estimation of central venous pressure through measurement of the inferior vena cava. More advanced techniques such as right ventricular function, diastology, and valvular assessments are sometimes employed by those with further training, especially in more remote or higher-acuity clinical environments.

      Pediatric and Neonatal Medicine

      While there is overlap between POCUS applications in pediatric and adult patients, cardiac POCUS in children must consider the unique physiologic changes that occur during development, especially in the immediate postnatal period. During this period, systemic vascular resistance increases drastically as the placenta is taken out of the circuit, while pulmonary resistance falls as the infant takes their first breaths. At the same time, shunts that served important purposes in utero, such as the foramen ovale and the ductus arteriosus, must close.
      • Mertens L
      • Seri I
      • Marek J
      • et al.
      Targeted neonatal echocardiography in the neonatal intensive care unit: practice guidelines and recommendations for training. Writing Group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC).
      This makes cardiac POCUS in the neonatal intensive care unit a dynamic challenge. Furthermore, standardized curricula and training pathways in cardiac POCUS do not exist for general pediatricians, pediatric hospitalists, or neonatal and pediatric intensive care providers. As a result, multiple international societies have collaborated to provide expert guidelines.
      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      ,
      • Mertens L
      • Seri I
      • Marek J
      • et al.
      Targeted neonatal echocardiography in the neonatal intensive care unit: practice guidelines and recommendations for training. Writing Group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC).
      These societies agree that structural, congenital defects suspected on POCUS should be referred to pediatric cardiologists (Table).
      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      ,
      • Mertens L
      • Seri I
      • Marek J
      • et al.
      Targeted neonatal echocardiography in the neonatal intensive care unit: practice guidelines and recommendations for training. Writing Group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC).
      Assuming that the typical postnatal transition occurs without complication and congenital defects are not present, pediatric cardiac POCUS has many similarities with adult cardiac POCUS in its utility in cases of hemodynamic compromise. The same basic views are used to assess ventricular function, pericardial pathology, and central venous pressure. A qualitative “eyeball” assessment may be used to assess ventricular function. More advanced users may employ semi-quantitative measures such as fractional shortening, ejection fraction, stroke volume, mitral annular plane systolic excursion, and end-point septal separation, although it is important to note that several of these measures must be compared with age-appropriate Z-scores and that end-point septal separation is only validated in adults.
      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      As in adults, the presence of pericardial effusion should be evaluated with multiple cardiac views and pericardiocentesis should be guided by ultrasound. Measurement of right atrial pressure using the inferior vena cava is slightly different in the pediatric population, as the short-axis view is the view most studied in the pediatric population because it allows side-by-side comparison with aortic dimensions.
      • Chen L
      • Kim Y
      • Santucci KA
      Use of ultrasound measurement of the inferior vena cava diameter as an objective tool in the assessment of children with clinical dehydration.
      • Kwon H
      • Jung JY
      • Lee JH
      • et al.
      Sonographic aorta/IVC cross-sectional area index for evaluation of dehydration in children.
      • Choi YA
      • Kwon H
      • Lee JH
      • Jung JY
      • Choi YJ
      Comparison of sonographic inferior vena cava and aorta indexes during fluid administered in children.
      • Long E
      • Oakley E
      • Duke T
      • Babl FE
      Paediataric Research in Emergency Departments International Collaborative
      Does respiratory variation in inferior vena cava diameter predict fluid responsiveness: a systematic review and meta-analysis.
      The same caveats apply in both populations, and a meta-analysis showed that inferior vena cava collapsibility has only moderate ability to predict fluid responsiveness in children.
      • Long E
      • Oakley E
      • Duke T
      • Babl FE
      Paediataric Research in Emergency Departments International Collaborative
      Does respiratory variation in inferior vena cava diameter predict fluid responsiveness: a systematic review and meta-analysis.
      In addition, the inferior vena cava becomes an unreliable measure of right atrial pressure when an umbilical central venous catheter is present, as is the case in many infants in the neonatal intensive care unit.
      • Singh Y
      • Tissot C
      • Fraga MV
      • et al.
      International evidence-based guidelines on point of care ultrasound (POCUS) for critically ill neonates and children issued by the POCUS Working Group of the European Society of Paediatric and Neonatal Intensive Care (ESPNIC).
      There are no minimal training pathway requirements for the application of cardiac POCUS by pediatricians, although advanced guidelines do exist (Table).

      Anesthesiology

      Anesthesiologists use POCUS, including cardiac POCUS, to complement the physical examination by obtaining information in real time to guide hemodynamic management and make more accurate differential diagnoses to rule out life-threatening conditions. The American Society of Anesthesia and the Society of Cardiovascular Anesthesiologists described ultrasound examinations’ current and potential targets, as well as its use for estimation, evaluation, and potential procedural guidance for many applications, including cardiac (Table).
      • Mahmood F
      • Matyal R
      • Skubas N
      • et al.
      Perioperative ultrasound training in anesthesiology: a call to action.
      Cardiac POCUS is not intended to be a comprehensive examination; in addition, most of the POCUS studies in the operating room are performed with small devices that do not have complete packages or capability for advanced analysis. On the other hand, using small devices adds the benefit of portability, more now that handheld devices are widely available and accessible.
      • Coker BJ
      • Zimmerman JM
      Why anesthesiologists must incorporate focused cardiac ultrasound into daily practice.
      Many anesthesiology training programs incorporate a POCUS rotation for their residents.
      • Conlin F
      • Connelly NR
      • Raghunathan K
      • Friderici J
      • Schwabauer A
      Focused transthoracic cardiac ultrasound: a survey of training practices.
      ,
      • Meineri M
      • Bryson GL
      • Arellano R
      • Skubas N
      Core point-of-care ultrasound curriculum: what does every anesthesiologist need to know?.
      The Accreditation Council for Graduate Medical Education, American Board of Anesthesiology, and the Canadian Anesthesia Society encourage the integration of POCUS in the field of anesthesia as a core competency.
      • Meineri M
      • Arellano R
      • Bryson G
      • et al.
      Canadian recommendations for training and performance in basic perioperative point-of-care ultrasound: recommendations from a consensus of Canadian anesthesiology academic centres.
      ,
      • Bronshteyn YS
      • Anderson TA
      • Badakhsh O
      • et al.
      Diagnostic point-of-care ultrasound: recommendations from an expert panel.
      • Kalagara H
      • Manson W
      • Townsley MM
      Point-of-care ultrasound (pocus) training for anesthesiologists: is it time to embrace and attain competency?.
      • Millington SJ
      Consensus guidelines for perioperative point-of-care ultrasound: the devil is in the (implementation) details.

      Critical Care Medicine

      Basic cardiac POCUS is part of the training curriculum for critical care medicine in Australia and Europe,
      • Flower L
      • Dempsey M
      • White A
      • Sanfilippo F
      • Olusanya O
      • Madhivathanan PR
      Training and accreditation pathways in critical care and perioperative echocardiography.
      ,
      • Póvoa P
      • Martin-Loeches I
      • Duska F
      CoBaTrICE Collaboration
      Updated competency-based training in intensive care: next step towards a healthcare union in Europe?.
      with India
      • Srinivasan S
      • Kumar PG
      • Govil D
      • et al.
      Competencies for point-of-care ultrasonography in ICU: an ISCCM expert panel practice recommendation.
      and Canada
      • Arntfield RT
      • Millington SJ
      • Ainsworth CD
      • et al.
      Canadian recommendations for critical care ultrasound training and competency.
      having guidelines in place. Australia, France, Europe, the United States, and the UK have advanced accreditations specifically in “critical care echocardiography.”
      • Flower L
      • Dempsey M
      • White A
      • Sanfilippo F
      • Olusanya O
      • Madhivathanan PR
      Training and accreditation pathways in critical care and perioperative echocardiography.
      Critical care echocardiography differs from cardiac POCUS in that users are trained in techniques such as spectral Doppler to make advanced hemodynamic determinations with advanced cardiac views. More recently, the National Board of Echocardiography, in collaboration with the American College of Chest Physicians, the American Thoracic Society, the Society of Critical Care Medicine, the National Board of Medical Examiners, and other partner societies, developed an Examination of Special Competence in Critical Care Echocardiography (known as CCEeXAM).
      • Mayo PH
      • Narasimhan M
      • Koenig S
      Advanced critical care echocardiography: the intensivist as the ACCE of hearts.

      Nephrology

      Nephrologists practice in a diverse array of settings, including outpatient clinics, hospital wards, intensive care units, outpatient dialysis centers, and home dialysis centers. Accordingly, cardiac POCUS with assessment left ventricular ejection fraction, pericardial effusion, relative right ventricular size, and inferior vena cava size and collapsibility is helpful across multiple practice settings, such as evaluation for cardiorenal syndrome in a patient with new chronic kidney disease in an outpatient nephrology practice, evaluation of hemodialysis patient with intradialytic hypotension, and rapidly differentiating etiologies of shock in critical care nephrology.
      • Koratala A
      • Bhattacharya D
      • Kazory A
      Point of care renal ultrasonography for the busy nephrologist: a pictorial review.
      For patients with acute kidney injury or end-stage kidney disease on any dialysis modality, nephrologists are assessing volume status sometimes multiple times per day and assessing response to ultrafiltration. The physical examination is remarkably insensitive and unspecific for the detection of volume excess, so POCUS evaluation of volume status, including cardiac POCUS, adds critical and timely information.
      • Torino C
      • Gargani L
      • Sicari R
      • et al.
      The agreement between auscultation and lung ultrasound in hemodialysis patients: the LUST study.
      ,
      • Argaiz ER
      • Koratala A
      • Reisinger N
      Comprehensive assessment of fluid status by point-of-care ultrasonography.
      For these reasons, uptake of POCUS has been increasing in recent years, with 38% of nephrology training programs having implemented a POCUS curriculum and fully 95% of nephrology training programs planning on incorporating POCUS in future years.
      • Moore CA
      • Ross DW
      • Pivert KA
      • Lang VJ
      • Sozio SM
      • O'Neill WC
      Point-of-care ultrasound training during nephrology fellowship: a national survey of fellows and program directors.
      The main barrier is lack of trained faculty.
      • Moore CA
      • Ross DW
      • Pivert KA
      • Lang VJ
      • Sozio SM
      • O'Neill WC
      Point-of-care ultrasound training during nephrology fellowship: a national survey of fellows and program directors.
      To fill this demand, major nephrology and kidney care organizations have organized stand-alone POCUS programs for fellows and faculty.
      • Reisinger NC
      • Koratala A
      Incorporating training in POCUS in nephrology fellowship curriculum.
      Increasingly, early career nephrologists interested in POCUS in nephrology are undertaking 1-year clinical ultrasound fellowships to become thought leaders and site directors (Table).
      • Baston CM
      • Wallace P
      • Chan W
      • Dean AJ
      • Panebianco N
      Innovation through collaboration: creation of a combined emergency and internal medicine point-of-care ultrasound fellowship.

      Remote and Rural Medicine

      Ninety-seven percent of the geographic United States is considered nonurban or rural, which accounts for low-population-density regions containing approximately 19% of the population.

      US Census Bureau. 2011-2015 ACS 5-year estimates. Available at:https://www.census.gov/programs-surveys/acs/technical-documentation/table-and-geography-changes/2015/5-year.html. Accessed November 3, 2022.

      On average, the rural population is older, with a lower level of education and higher rates of being uninsured. Compared with those living in urban areas, rural residents have higher rates of mortality from heart disease, respiratory disease, cancer, stroke, and unintentional injury, and thus represent a high-risk population with significant illness burden.

      Council on Graduate Medical Education (COGME). Rural Health Policy Brief 1: special needs in rural America: implications for healthcare workforce education, training, and practice. 2020. Available at:https://www.hrsa.gov/sites/default/files/hrsa/advisory-committees/graduate-medical-edu/publications/cogme-rural-health-policy-brief.pdf. Accessed December 12, 2022.

      Transport time, travel distance, transport cost, and risk of transfer increases in these communities. Available tertiary care centers with bed capacity may be limited for these hospitals and rural systems. Availability of echocardiograms and formal cardiology consultation options decrease the further the distance away from urban centers, and providers working in these areas require a broad skill set. In the United States, widespread implementation of cardiac POCUS programs in rural health face many challenges. Barriers include access to training, mentorship, and equipment. In Canada, the Accelerated Remote Consultation Tele-POCUS in Cardiopulmonary Assessment program links tertiary hubs with geographically remote "spoke" regions to provide tele-mentorship of Tele-POCUS skills for physicians that previously did not have access to such imaging training or implementation.
      • Lam J
      • Wong S
      • Grubic N
      • et al.
      Accelerated Remote Consultation Tele-POCUS in Cardiopulmonary Assessment (ARCTICA).
      Some of the most isolated, rural, or resource-poor providers would have the greatest benefit from an advanced skill set in advanced cardiac POCUS, given severe resource limitations. In rural areas, there often is a great sense of tension between the acceptance of limited diagnostic evidence and limited interventional options, weighed against the systemic or patient-borne cost of obtaining timely advanced diagnostic evaluation and advanced management. Greater skill set in advanced cardiac POCUS can help to bridge these competing tensions.

      Conclusion

      Cardiac POCUS is a form of cardiovascular ultrasound that is performed at the bedside by the patient's medical provider, usually to answer an immediate question. Cardiac POCUS has evolved, in part, due to barriers to entry falling due to technologic advances such as miniaturization, and it is anticipated to continue additional advances such as artificial or augmented intelligence and Tele-POCUS. Currently, many medical specialists are performing cardiac POCUS, and its use continues to expand into diverse disciplines such as pediatrics, anesthesiology, and nephrology. Generalist physicians in both internal and family medicine use cardiac POCUS across the inpatient and outpatient settings. Several specialty areas have developed training or credentialing methods for their domains to support this use, yet these continue to remain undefined for a large proportion of current users. There appears to be a trend toward cardiac POCUS training beginning in medical training prior to specialization as an emerging general competency, which should assist in competency building for all, but this, too, currently lacks standards and guidelines.

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