Advertisement

CME: Is it Meeting the Mark?

      Continuing medical education (CME) is widespread in many countries, including the United States. CME “consists of educational activities which serve to maintain, develop, or increase the knowledge, skills, and professional performance and relationships that a physician uses to provide services for patients, the public, or the profession.”

      Accreditation Council for Continuing Medical Education (ACCME). CME content: definition and examples. Available at:https://www.accme.org/accreditation-rules/policies/cme-content-definition-and-examples. Accessed January 4, 2023.

      The rapid advancement of research and technology in today's world that influences clinical practice increases the need for effective CME programs.
      • Fletcher SW
      Continuing education in the health professions: improving healthcare through lifelong learning.
      This commentary will consider the effectiveness of CME, focusing on its structure and funding sources.

      Is CME Effective? – Structure of Program

      The format of CME has been shown to influence its effectiveness in delivering content to physicians. CME can take multiple forms: from the conventional, passive lecture format to more interactive sessions. A study involving a survey of academic CME leaders in the United States and Canada reported that lectures were still the most widely adopted platform for delivering content in CME programs. However, didactic CME interventions have not shown success in impacting physician behavior or patient outcomes, although they can influence knowledge, skills, and attitudes.
      • Davis D
      • O'Brien MAT
      • Freemantle N
      • Wolf FM
      • Mazmanian P
      • Taylor-Vaisey A
      Impact of formal continuing medical education do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes?.
      These ineffective CME structures continue to be adopted, potentially due to the barriers to adopt active learning techniques that are more likely to be effective. These include the increased effort in preparing and organizing interactive sessions compared with didactic lectures.
      • Bucklin BA
      • Asdigian NL
      • Hawkins JL
      • Klein U
      Making it stick: use of active learning strategies in continuing medical education.
      In addition, physicians themselves prefer to engage in traditional lecture CME sessions than more interactive ones. One proposed reason for this misalignment in the popularity and the effectiveness of the course structure is that interactive sessions can make physicians feel more uncomfortable with greater opportunities to “stand out.”
      • Stephens MB
      • McKenna M
      • Carrington K
      Adult learning models for large-group continuing medical education activities.
      The effectiveness of interactive CME is difficult to conclusively determine. Although the evidence on increased support for interactive over traditional CME is clear from multiple systematic reviews and evidence on active learning strategies, the effectiveness of interactive CME on the more salient endpoints of physician behavior and patient outcomes, especially, is unclear.
      • Stephens MB
      • McKenna M
      • Carrington K
      Adult learning models for large-group continuing medical education activities.
      • Raza A
      • Coomarasamy A
      • Khan KS
      Best evidence continuous medical education.
      • Cervero RM
      • Gaines JK
      The impact of CME on physician performance and patient health outcomes: an updated synthesis of systematic reviews.
      Systematic reviews present differing conclusions on the impact of interactive CME due to differences in their definition of CME interventions.
      • Cervero RM
      • Gaines JK
      The impact of CME on physician performance and patient health outcomes: an updated synthesis of systematic reviews.
      For instance, a Cochrane systematic review had a restrictive definition of CME that only included courses, conferences, lectures, workshops, seminars, and symposia, while another review included educational outreach, auditing, group discussions, and online platforms.
      • Forsetlund L
      • O'Brien MA
      • Forsén L
      • et al.
      Continuing education meetings and workshops: effects on professional practice and healthcare outcomes.
      ,
      • Marinopoulos SS
      • Dorman T
      • Ratanawongsa N
      • et al.
      Effectiveness of continuing medical education.
      In the Cochrane analysis, among 215 studies examined, 6 sought to ascertain if CME activities were associated with differences in provider behavior, prescribing, or demeanor.
      • Forsetlund L
      • O'Brien MA
      • Forsén L
      • et al.
      Continuing education meetings and workshops: effects on professional practice and healthcare outcomes.

      Is CME Effective? – Marketing and Bias

      The industry-derived funding sources of CME question their validity and objectivity. According to the Accreditation Council for Continuing Medical Education (ACCME) 2020 report, 10% of CME courses are currently funded by drug and device manufacturers, which have the incentive to promote products and practices that increase their company's profits rather than those that are the best for patients.

      Accreditation Council for Continuing Medical Education (ACCME). Annual data reports. Available at: https://www.accme.org/data-reports. Accessed January 6, 2023.

      Firstly, the involvement of industries can cause market creation. In Medicine, this is termed as “condition branding.”
      • Meixel A
      • Yanchar E
      • Fugh-Berman A
      Hypoactive sexual desire disorder: inventing a disease to sell low libido.
      With intensive marketing strategies, companies can frame conditions as diseases. For instance, CME (with the financial support from companies) has been used as a tool to frame aging as a disease to increase the need for hormone formulations.
      • Fugh-Berman AJ
      The haunting of medical journals: how ghostwriting sold “HRT”.
      Excessive marketing becomes more problematic where it can promote products that are yet to be approved by regulators. Examples include gabapentin, an anti-epilepsy drug that was promoted to be repurposed for migraines and other disorders.
      • Steinman MA
      • Bero LA
      • Chren MM
      • Landefeld CS
      Narrative review: the promotion of gabapentin: an analysis of internal industry documents.
      Marketing strategies can also include more subtle methods of funding influencers. Although influencers may not publicly advertise a product, they can contribute to “condition branding.”
      • Fugh-Berman A
      Industry-funded medical education is always promotion—an essay by Adriane Fugh-Berman.
      Secondly, the involvement of profit-driven companies can cause the downplaying or complete neglect of harms of products. This is best seen in the case of opioids. Opioid manufacturers have used CME as a tool in promoting use of fentanyl products for conditions such as migraines, and injuries.
      • Infeld M
      • Bell A
      • Marlin C
      • Waterhouse S
      • Uliassi N
      • Fugh-Berman A
      Continuing medical education and the marketing of fentanyl for breakthrough pain: marketing messages in an industry-funded CME module on breakthrough pain.
      Individuals exposed to content from industry-funded CME materials were shown to neglect the possibility of addiction or other side effects of opioid use, which was recognized by those exposed to non-industry-funded CME materials.
      • Infeld M
      • Bell A
      • Marlin C
      • Waterhouse S
      • Uliassi N
      • Fugh-Berman A
      Continuing medical education and the marketing of fentanyl for breakthrough pain: marketing messages in an industry-funded CME module on breakthrough pain.
      Other examples where industry-funded CME has falsely minimized the harms and focused on the benefits include binge-eating disorder, menopausal hormone therapy, and testosterone therapy.
      • Jung J
      • Fugh-Berman A
      Marketing messages in continuing medical education (CME) modules on binge-eating disorder (BED).
      Despite the active role of ACCME in regulating the role of industry in CME courses, some experts argue that these regulators aid in the masking of industry involvement in CME.
      • Fugh-Berman A
      Industry-funded medical education is always promotion—an essay by Adriane Fugh-Berman.
      Although the ACCME reports that industry-backed CME makes a small proportion of the total today, this could be an underreporting, with ACCME's move to stop counting “equipment, supplies, and facilities” among other resources as commercial support. Despite the seeming decrease in industry-funded CME programs over the years, their subtle involvement is only anticipated to increase in the future, with medical centers and hospitals aiming to stop funding CME for surgeons in 2022. This is reinforced with the preference of surgical residents for free CME opportunities that are more likely with commercial company-backed opportunities.
      • Rüetschi U
      • Olarte Salazar CM
      An e-Delphi study generates expert consensus on the trends in future continuing medical education engagement by resident, practicing, and expert surgeons.

      Conclusion

      The effectiveness of CME depends on its structure. While the evidence that CME impacts short-term knowledge assessments is strong; the evidence it changes provider behavior, specifically with the goal of improving patient safety and outcomes, is weak. With the increased importance of CME, it is essential to explore strategies to organize effective programs that have reduced, or no, bias from industries.
      • Schulte TL
      • Gröning T
      • Ramsauer B
      • et al.
      Impact of COVID-19 on continuing medical education—results of an online survey among users of a non-profit multi-specialty live online education platform.
      In organizing effective CME programs, the role of online platforms, which have grown in popularity since the COVID-19 pandemic, should be considered. In achieving reduced or no bias from companies, it can be important to develop methods to identify subtle biases with the existence of 3 instruments to evaluate explicit bias in CME programs.
      • Takhar J
      • Dixon D
      • Donahue J
      • et al.
      Developing an instrument to measure bias in CME.
      • Barnes BE
      • Cole JG
      • King CT
      • et al.
      A risk stratification tool to assess commercial influences on continuing medical education.
      • Price D
      • Havens C
      • Bellman P
      Audience assessment of bias in continuing medical education programs.

      References

      1. Accreditation Council for Continuing Medical Education (ACCME). CME content: definition and examples. Available at:https://www.accme.org/accreditation-rules/policies/cme-content-definition-and-examples. Accessed January 4, 2023.

        • Fletcher SW
        Continuing education in the health professions: improving healthcare through lifelong learning.
        J Contin Educ Nurs. 2008; 39: 112-118
        • Davis D
        • O'Brien MAT
        • Freemantle N
        • Wolf FM
        • Mazmanian P
        • Taylor-Vaisey A
        Impact of formal continuing medical education do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes?.
        JAMA. 1999; 282: 867-874
        • Bucklin BA
        • Asdigian NL
        • Hawkins JL
        • Klein U
        Making it stick: use of active learning strategies in continuing medical education.
        BMC Med Educ. 2021; 21: 44
        • Stephens MB
        • McKenna M
        • Carrington K
        Adult learning models for large-group continuing medical education activities.
        Fam Med. 2011; 43: 334-337
        • Raza A
        • Coomarasamy A
        • Khan KS
        Best evidence continuous medical education.
        Arch Gynecol Obstet. 2009; 280: 683-687
        • Cervero RM
        • Gaines JK
        The impact of CME on physician performance and patient health outcomes: an updated synthesis of systematic reviews.
        J Contin Educ Health Prof. 2015; 35: 131-138
        • Forsetlund L
        • O'Brien MA
        • Forsén L
        • et al.
        Continuing education meetings and workshops: effects on professional practice and healthcare outcomes.
        Cochrane Database Syst Rev. 2021; 9CD003030
        • Marinopoulos SS
        • Dorman T
        • Ratanawongsa N
        • et al.
        Effectiveness of continuing medical education.
        Evid Rep Technol Assess (Full Rep). 2007; : 1-69
      2. Accreditation Council for Continuing Medical Education (ACCME). Annual data reports. Available at: https://www.accme.org/data-reports. Accessed January 6, 2023.

        • Meixel A
        • Yanchar E
        • Fugh-Berman A
        Hypoactive sexual desire disorder: inventing a disease to sell low libido.
        J Med Ethics. 2015; 41: 859-862
        • Fugh-Berman AJ
        The haunting of medical journals: how ghostwriting sold “HRT”.
        PLoS Med. 2010; 7e1000335
        • Steinman MA
        • Bero LA
        • Chren MM
        • Landefeld CS
        Narrative review: the promotion of gabapentin: an analysis of internal industry documents.
        Ann Intern Med. 2006; 145: 284-293
        • Fugh-Berman A
        Industry-funded medical education is always promotion—an essay by Adriane Fugh-Berman.
        BMJ. 2021; 373: n1273
        • Infeld M
        • Bell A
        • Marlin C
        • Waterhouse S
        • Uliassi N
        • Fugh-Berman A
        Continuing medical education and the marketing of fentanyl for breakthrough pain: marketing messages in an industry-funded CME module on breakthrough pain.
        World Med Health Policy. 2019; 11: 43-58
        • Jung J
        • Fugh-Berman A
        Marketing messages in continuing medical education (CME) modules on binge-eating disorder (BED).
        J Am Board Fam Med. 2020; 33: 240-251
        • Rüetschi U
        • Olarte Salazar CM
        An e-Delphi study generates expert consensus on the trends in future continuing medical education engagement by resident, practicing, and expert surgeons.
        Med Teach. 2020; 42: 444-450
        • Schulte TL
        • Gröning T
        • Ramsauer B
        • et al.
        Impact of COVID-19 on continuing medical education—results of an online survey among users of a non-profit multi-specialty live online education platform.
        Front Med (Lausanne). 2021; 8773806
        • Takhar J
        • Dixon D
        • Donahue J
        • et al.
        Developing an instrument to measure bias in CME.
        J Contin Educ Health Prof. 2007; 27: 118-123
        • Barnes BE
        • Cole JG
        • King CT
        • et al.
        A risk stratification tool to assess commercial influences on continuing medical education.
        J Contin Educ Health Prof. 2007; 27: 234-240
        • Price D
        • Havens C
        • Bellman P
        Audience assessment of bias in continuing medical education programs.
        J Contin Educ Health Prof. 2009; 29: 76