A 78-year-old man was admitted with a 2-year history of periodic fever of unknown etiology with frequent remissions and exacerbations of pericardial and pleural effusions. He had a history of tuberculosis at 22 years of age, and had no relevant family history. Chest radiography (CX-R) demonstrated cardiomegaly and left-sided pleural effusion (Figure 1A). Chest computed tomography revealed extensive pericardial effusion and left encapsulated pleural effusion (Figure 1B). Oxygen saturation was 92% on 2 L/min of oxygen. Based on the available clinical and radiological findings, the differential diagnosis encompassed malignant lymphoma, tuberculosis pleuropericarditis, collagen diseases, and autoinflammatory disorders such as familial Mediterranean fever.
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- Recent Developments in Pathogenesis and New Recommendations for Management.Front Immunol. 2017; 8: 253
- Attacks of pericarditis as a manifestation of familial Mediterranean fever (FMF).Qjm. 1997; 90: 643-647
- Late-onset familial Mediterranean fever in Japan.Mod Rheumatol. 2020; 30: 564-567
- Evaluation and Treatment of Pericarditis: A Systematic Review.Jama. 2015; 314: 1498-1506
- Efficacy of intermittent colchicine therapy in familial Mediterranean fever.Ann Intern Med. 1977; 86: 162-165
- Genotype Mutations in Egyptian Children with Familial Mediterranean Fever: Clinical Profile, and Response to Colchicine.Mediterr J Rheumatol. 2020; 31: 206-213
Accepted: January 26, 2023
Received: October 31, 2022
Publication stageIn Press Journal Pre-Proof
Conflict of interest: All authors declared no conflict of interest.
Authorship: All authors examined and treated the patient as one team, equally contributed to writing the manuscript, and had access to clinical information relevant to the described case.
© 2023 Published by Elsevier Inc.