Advertisement

Insomnia, Myalgia, and Heavy Proteinuria in a 41-Year-Old Woman

  • Bo Han
    Affiliations
    Bo Han, MD, Department of Nephrology, The Fifth Medical Center of PLA General Hospital, Poisoning Treatment Center of PLA, Beijing 100071, China
    Search for articles by this author
  • Lishuai Xiao
    Affiliations
    Lishuai Xiao, MD, Graduate School, Anhui Medical University, Hefei 230022, China
    Search for articles by this author
  • Xishan Xiong
    Correspondence
    Corresponding author: Xishan Xiong, Department of Nephrology, Affiliated Suzhou Municipal Hospital of Anhui Medical University, Suzhou 234000, China. Tel/fax: +86 0557-3023025
    Affiliations
    Xishan Xiong, MD, Department of Nephrology, Affiliated Suzhou Municipal Hospital of Anhui Medical University, Suzhou 234000, China
    Search for articles by this author
Published:November 07, 2022DOI:https://doi.org/10.1016/j.amjmed.2022.10.017
      Chronic mercury toxicity secondary to the use of inorganic mercury-containing skin-lightening creams is often misdiagnosed, mainly due to its non-specific symptoms.
      • Chan TYK
      • Chan APL
      • Tang HL.
      Nephrotic syndrome caused by exposures to skin-lightening cosmetic products containing inorganic mercury.
      Before a mercury toxicology workup was initiated, victims had been frequently seen by physicians in various specialties under the suspicion of many other diseases.
      • Wojcik DP
      • Godfrey ME
      • Christie D
      • Haley BE.
      Mercury toxicity presenting as chronic fatigue, memory impairment and depression: diagnosis, treatment, susceptibility, and outcomes in a New Zealand general practice setting (1994-2006).
      Despite the law prohibiting use of mercury in cosmetics beyond trace amounts, mercury-containing creams are still widely available in this era of easy travels and e-commerce.
      • Hamann CR
      • Boonchai W
      • Wen L
      • et al.
      Spectrometric analysis of mercury content in 549 skin-lightening products: is mercury toxicity a hidden global health hazard?.
      We herein describe a patient with neuropathy and nephropathy secondary to mercury poisoning who made a full recovery following the initiation of chelation therapy not in conjunction with corticosteroids.

      Key words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Chan TYK
        • Chan APL
        • Tang HL.
        Nephrotic syndrome caused by exposures to skin-lightening cosmetic products containing inorganic mercury.
        Clin Toxicol (Phila). 2020; 58: 9-15
        • Wojcik DP
        • Godfrey ME
        • Christie D
        • Haley BE.
        Mercury toxicity presenting as chronic fatigue, memory impairment and depression: diagnosis, treatment, susceptibility, and outcomes in a New Zealand general practice setting (1994-2006).
        Neuro Endocrinol Lett. 2006; 27: 415-423
        • Hamann CR
        • Boonchai W
        • Wen L
        • et al.
        Spectrometric analysis of mercury content in 549 skin-lightening products: is mercury toxicity a hidden global health hazard?.
        J Am Acad Dermatol. 2014; 70 (e283): 281-287