Bilateral pleural effusions as the initial manifestation of rheumatoid arthritis

Published:November 06, 2022DOI:
      Rheumatoid arthritis has a well-established association with pulmonary manifestations, including pleural effusions. However, only 3-5% of pleural effusions are known to be symptomatic and are frequently unilateral.
      • Shaw M
      • Collins BF
      • Ho LA
      • Raghu G.
      Rheumatoid arthritis-associated lung disease.
      Herein, we present an atypical case of a patient with respiratory failure found to have bilateral pleural effusions as the initial presenting manifestation of rheumatoid arthritis.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Shaw M
        • Collins BF
        • Ho LA
        • Raghu G.
        Rheumatoid arthritis-associated lung disease.
        Eur Respir Rev. 2015; 24: 1-16
        • Azam AT
        • Odeyinka O
        • Alhashimi R
        • Thoota S
        • Ashok T
        • Palyam V
        • et al.
        Rheumatoid Arthritis and Associated Lung Diseases: A Comprehensive Review.
        Cureus. 2022; 14: e22367
        • Kadura S
        • Raghu G.
        Rheumatoid arthritis-interstitial lung disease: manifestations and current concepts in pathogenesis and management.
        Eur Respir Rev. 2021; 30
        • Balbir-Gurman A
        • Yigla M
        • Nahir AM
        • Braun-Moscovici Y.
        Rheumatoid pleural effusion.
        Semin Arthritis Rheum. 2006; 35: 368-378
        • Avnon LS
        • Abu-Shakra M
        • Flusser D
        • Heimer D
        • Sion-Vardy N.
        Pleural effusion associated with rheumatoid arthritis: what cell predominance to anticipate?.
        Rheumatol Int. 2007; 27: 919-925
        • Yunt ZX
        • Solomon JJ.
        Lung disease in rheumatoid arthritis.
        Rheum Dis Clin North Am. 2015; 41: 225-236