Abstract
Introduction
This study aims to evaluate the accuracy of bedside assessment of inferior vena cava
(IVC) and right internal jugular (RIJ) vein in predicting right atrial (RA) pressure
in heart failure patients.
Methods
We prospectively studied 124 heart failure patients who were referred to our catheterization
laboratory for right heart catheterizations to assess hemodynamics and to guide heart
failure management. Just prior to the procedure, a handheld ultrasound examination
was performed in each patient. The volume status was assessed by estimating RA pressure
using end-expiratory IVC dimension, IVC respiratory collapsibility, and RIJ respiratory
collapsibility. Patients were divided into 2 groups based on invasive RA pressure
value. Multiple logistic regression models were used to identify factors associated
with RA ≥10 mm Hg; a 3-point simple score was then created. The performance of this
score was assessed using the receiver operating characteristics curve.
Results
In this study 124 heart failure patients were included; median age was 59 years (interquartile
range 48-65), and 40% were female. RIJ respiratory collapsibility <50%, end-expiratory
IVC dimension ≥21 mm, and respiratory collapsibility <50% were significantly associated
with elevated RA pressure, and were used to build the score. The area under the receiver
operating characteristics curve (AUC) for the 3-point score was 0.84 (0.77-0.92),
and it performed better than 2-point score using IVC characteristics alone (AUC 0.84
[0.77-0.92] vs 0.75 [0.67-0.83]; P = .003). Of 124 patients, 90 patients (72.5%) had concordant RA pressure and pulmonary
capillary wedge pressure.
Conclusion
Concomitant ultrasound assessment of RIJ and IVC correlated better with RA pressure
than IVC alone. A simple 3-point score can provide a useful and easily accessible
tool to estimate volume status, and further guide management of heart failure patients.
Keywords
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References
- Physical examination of venous pressure: a critical review.Am Heart J. 1998; 136: 10-18
- Clinical evaluation compared to pulmonary artery catheterization in the hemodynamic assessment of critically ill patients.Crit Care Med. 1984; 12: 549-553
- A comparison by medicine residents of physical examination versus hand-carried ultrasound for estimation of right atrial pressure.Am J Cardiol. 2007; 99: 1614-1616
- Noninvasive evaluation of right atrial pressure.J Am Soc Echocardiogr. 2013; 26: 1033-1042
- International evidence-based recommendations for focused cardiac ultrasound.J Am Soc Echocardiogr. 2014; 27: 683.e1-683.e33
- Noninvasive estimation of right atrial pressure from the inspiratory collapse of the inferior vena cava.Am J Cardiol. 1990; 66: 493-496
- IVC diameter in patients with chronic heart failure: relationships and prognostic significance.JACC Cardiovasc Imaging. 2013; 6: 16-28
- Reappraisal of the use of inferior vena cava for estimating right atrial pressure.J Am Soc Echocardiogr. 2007; 20: 857-861
- Relation of mean right atrial pressure to echocardiographic and Doppler parameters of right atrial and right ventricular function.Circulation. 1996; 93: 1160-1169
- Correlation of sonographic measurements of the internal jugular vein with central venous pressure.Am J Emerg Med. 2009; 27: 851-855
- Ultrasound accurately reflects the jugular venous examination but underestimates central venous pressure.Chest. 2011; 139: 95-100
- The sensitivity and specificity of ultrasound estimation of central venous pressure using the internal jugular vein.J Crit Care. 2012; 27: 315.e7-315.e11
- Detection of elevated right atrial pressure using a simple bedside ultrasound measure.Am Heart J. 2010; 159: 421-427
- Bedside ultrasound assessment of jugular venous compliance as a potential point-of-care method to predict acute decompensated heart failure 30-day readmission.J Am Heart Assoc. 2018; 7e008184
- Guidelines for the use of echocardiography as a monitor for therapeutic intervention in adults: a report from the American Society of Echocardiography.J Am Soc Echocardiogr. 2015; 28: 40-56
- Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography. Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography.J Am Soc Echocardiogr. 2010; 23: 685-713
- Assessment of right atrial pressure with 2-dimensional and Doppler echocardiography: a simultaneous catheterization and echocardiographic study.Mayo Clin Proc. 2000; 75: 24-29
- Hand carried ultrasound measurement of inferior vena cava for assessment of intravascular volume status in the outpatient hemodialysis clinic.Clin J Am Soc Nephrol. 2006; 1: 749-753
- The efficacy of sonographic measurement of inferior vena cava diameter as an estimate of central venous pressure.Cardiovasc Ultrasound. 2016; 14: 33
- Rehospitalization for heart failure: problems and perspectives.J Am Coll Cardiol. 2013; 61: 391-403
- Inferior vena cava parameters predict re-admission in ischaemic heart failure.Eur J Clin Invest. 2014; 44: 341-349
- Comparison of hand-carried ultrasound assessment of the inferior vena cava and N-terminal pro-brain natriuretic peptide for predicting readmission after hospitalization for acute decompensated heart failure.JACC Cardiovasc Imaging. 2008; 1: 595-601
- Relationship between right and left-sided filling pressures in 1000 patients with advanced heart failure.J Heart Lung Transplant. 1999; 18: 1126-1132
- The relationship of right- and left-sided filling pressures in patients with heart failure and a preserved ejection fraction.Circ Heart Fail. 2010; 3: 202-206
- Mismatch of right- and left-sided filling pressures in chronic heart failure.J Card Fail. 2011; 17: 561-568
Article Info
Publication History
Published online: December 30, 2021
Footnotes
Funding: None.
Conflicts of Interest: None.
Authorship: All authors have access to the data and have made substantial contributions to the study design, data analysis and interpretation, and drafting the article, and all approved the final version.
Identification
Copyright
© 2021 Elsevier Inc. All rights reserved.