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Funding: AA was in part supported by the National Institutes of Health through grants ( R01-HL085561 , R01-HL085561-S and R01-HL097047 ) from the National Heart, Lung, and Blood Institute , and by the Department of Veterans Affairs Office of Research and Development grant through a grant ( I01HX002422 ) from the Health Services Research & Development Service .
Conflicts of Interest: GCF reports consulting with Abbott, Amgen, Astra Zeneca, Bayer, CHF Solutions, Cytokinetics, Edwards, Janssen, Medtronic, Merck, and Novartis and was the principal investigator of OPTIMIZE-HF. GlaxoSmithKline sponsored OPTIMIZE-HF but played no role in the design, conduct, analyses, or interpretation of the current study. EB, PHL, RE, CA, HMS, VB, CYJ, PD, CF, RMA, AA report none. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Department of Veterans Affairs.
Authorship: All authors had access to the data and a role in writing this manuscript.