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Funding: No specific funding was obtained for this study. EK holds a research position funded by the regional agreement on medical training and clinical research between Stockholm County Council and the Karolinska Institute (Grant number: 20190354 ). AR holds a research position funded by the Stockholm County Council (Grant number: 20200935 ). US is supported by the Swedish Heart-Lung Foundation (Grant numbers 20180400 and 20190533 ). MJH holds research positions funded by the Swedish Heart-Lung Foundation (Grant number: 20170804 ) and the Stockholm County Council (Grant number: 20170686 ). The sponsors had no role in the design or conduct of this study.
Conflicts of Interest: MJH reports consultancy honoraria from Idorsia. EK, AR, AJS, US report none.
Authorship: All authors had access to the data and a role in writing this manuscript.