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Malignant Catatonia: Sepsis or Psychiatric Emergency?

      Malignant catatonia is a potentially fatal subtype of catatonia characterized by mutism, rigidity, stereotypy, autonomic dysfunction, and delirium.
      • Fink M
      • Taylor MA.
      The catatonia syndrome: forgotten but not gone.
      Although it is similar to neuroleptic malignant syndrome (NMS), it is classically associated with depression and psychosis rather than with use of psychotropic medications. Brain imaging may reveal frontal atrophy, and nonspecific lab findings are common.
      • Mann S
      • Caroff S
      • Campbell EC.
      Malignant catatonia.
      Treatment typically includes short-term benzodiazepines, followed by electroconvulsive therapy (ECT).
      • Fink M.
      Rediscovering catatonia: the biography of a treatable syndrome.
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      References

        • Fink M
        • Taylor MA.
        The catatonia syndrome: forgotten but not gone.
        Arch Gen Psychiatry. 2009; 66: 1173-1177https://doi.org/10.1001/archgenpsychiatry.2009.141
        • Mann S
        • Caroff S
        • Campbell EC.
        Malignant catatonia.
        in: Frucht S Fahn S Current Clinical Neurology. Humana Press, Totowa, NJ2005: 53
        • Fink M.
        Rediscovering catatonia: the biography of a treatable syndrome.
        Acta Psychiatr Scand Suppl. 2013; : 1-47https://doi.org/10.1111/acps.12038
        • Fink M
        • Taylor MA.
        The many varieties of catatonia.
        Eur Arch Psychiatry Clin Neurosci. 2001; 251: I8-13https://doi.org/10.1007/pl00014200
        • Hawkins JM
        • Archer KJ
        • Strakowski SM
        • Keck PE.
        Somatic treatment of catatonia.
        Int J Psychiatry Med. 1995; 25: 345-369https://doi.org/10.2190/X0FF-VU7G-QQP7-L5V7