Abstract
Studies evaluating fish consumption and cardiovascular disease events have shown inconsistent
results. We performed a systematic review of peer-reviewed publications from an extensive
query of Ovid MEDLINE, Ovid Embase, Ovid Cochrane Database of Systematic Reviews,
Scopus, and Web of Science from database inception to September 2020 for observational
studies that reported the association between fish consumption and cardiovascular
disease events. We identified and reviewed 24 studies related to fish consumption
and the effect on cardiovascular outcomes. The study population included a total of
714,526 individuals and multiple cohorts from several countries. We found that nonfried
fish consumption is probably associated with a reduced risk of overall cardiovascular
disease events and myocardial infarction risk. In contrast, fried fish consumption
is probably associated with an increased risk of overall cardiovascular disease events
and myocardial infarction risk. No studies to date have shown any significant association
between fish consumption and stroke. Our analysis suggests that fish consumption may
reduce cardiovascular disease events, but fried fish consumption was associated with
an increased risk of cardiovascular events.
Keywords
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Article Info
Publication History
Published online: January 11, 2021
Footnotes
Funding: None.
Conflict of Interest: CK discloses the following relationships – Member of the American College of Cardiology Solution Set Oversight Committee, The Lancet Digital Health (Advisory Board), European Heart Journal Digital Health (Editorial board) and Journal of the American Heart Association (Editorial board); The Journal of Scientific Innovation in Medicine (Associate Editor). SSV discloses the following relationships: Research support: Department of Veterans Affairs, World Heart Federation, Tahir and Jooma Family Honorarium: American College of Cardiology (Associate Editor for Innovations, acc.org).
Authorship: All authors had access to the data, contributed significantly to the work and a role in writing the manuscript.
Identification
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