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Funding: The Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study was supported by the Pharmacogenomics Research Network grant U01-GM074492 and the National Institute of Health National Center for Advancing Translational Sciences under the award number UL1 TR000064 (University of Florida), UL1 TR000454 (Emory University), and UL1 TR000135 (Mayo Clinic). The PEAR study was also supported by funds from the Mayo Foundation. LMSC received the predoctoral fellowship grant 20PRE35210065 from the American Heart Association. The funders/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. The content is solely the responsibility of the authors and does not represent the official views of the National Institutes of Health or the American Heart Association.
Conflict of Interest: None.
Authorship:All the authors had access to data and a role in writing this manuscript. LMSC: conceptualization, methodology, formal analysis, writing – original draft preparation, visualization, funding acquisition; AC: conceptualization, funding acquisition, writing – review & editing; JG: conceptualization, funding acquisition, writing – review & editing; RC-D: conceptualization, funding acquisition, writing – review & editing; JJ: conceptualization, methodology, funding acquisition, writing – review & editing, supervision. All authors read and approved the final manuscript. The PEAR and PEAR-2 study data are available under dbGaP Accession: phs000649.v2.p2 at https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000649.v2.p2. Any data not available in dbGaP can be obtained through request to the corresponding author.