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Funding: This study was self-funded by the Institute for Applied Health Research Berlin – InGef.
Conflicts of Interest: NS left InGef and joined Bayer AG after conduct of the study, except for the revision of the manuscript during the peer-review process, all work by NS was performed under InGef affiliation. EG as employee of the Leibniz Institute for Prevention Research and Epidemiology – BIPS has performed research studies paid by pharmaceutical companies (Bayer-Schering, GSK, Novartis, Sanofi-Pasteur, Takeda) unrelated to this study and has been consultant to Bayer, Takeda, GSK, Astellas, AstraZeneca on topics unrelated to the subject of this study. DE, JW, and AD report none.
Authorship: All authors had access to the data and a role in writing this manuscript.