Abstract
Introduction
Edible mushrooms have a great nutritional value including high protein, essential
amino acids, fiber, vitamins (B1, B2, B12, C, and D), minerals (calcium [Ca], potassium [K], magnesium [Mg], sodium [Na], phosphorus
[P], copper [Cu], iron [Fe], manganese [Mn], and selenium [Se]), low fatty foods,
and sodium. The objective of this systematic review was to determine the relationship
between edible mushroom consumption and overall cardiovascular risk.
Methods
We systematically searched Ovid MEDLINE, Embase, Ovid Cochrane Database of Systematic
Reviews, Scopus, and Web of Science from database inception from 1966 through August
2020 for observational studies that reported the association between edible mushroom
consumption and cardiovascular risk. Two investigators independently reviewed data.
Conflicts were resolved through consensus discussion.
Results
Of 1479 studies, we identified 7 prospective studies. Edible mushroom consumption
may have favorable effects on lipid profiles by changing some metabolic markers such
as low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol,
total cholesterol, and triglycerides. Moreover, edible mushroom consumption is probably
associated with reduced mean blood pressure. The beneficial overall cardiovascular
risk, stroke risk, and coronary artery disease of edible mushroom consumption are
not consistent.
Conclusions
Edible mushroom consumption has not been shown to conclusively affect cardiovascular
risk factors to date. However, potential health benefits may exist, including a favorable
alteration of lipid profiles and blood pressure reduction.
Keywords
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Article Info
Publication History
Published online: December 09, 2020
Footnotes
Funding: None.
Conflicts of Interest: CK reports being a member of the American College of Cardiology Solution Set Oversight Committee and The ACCF/AHA Task Force on Performance Measures, being on the Lancet Digital Health (Advisory Board), the European Heart Journal Digital Health (Editorial board), and the Journal of the American Heart Association (Editorial board); and serving the Journal of Scientific Innovation in Medicine (Associate Editor). SSV reports receiving research support: Department of Veterans Affairs, World Heart Federation, Tahir and Jooma Family Honorarium: American College of Cardiology (Associate Editor for Innovations, acc.org). AI, JH, ZW, SEF, DB, HJ, WHWT report none.
Authorship: All authors had access to the data and a role in writing this manuscript.
Identification
Copyright
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