Advertisement

Not Quite a Mono Spot Diagnosis. Splenic Infarction Complicating Infectious Mononucleosis

Published:November 17, 2020DOI:https://doi.org/10.1016/j.amjmed.2020.10.025
      A previously healthy 19-year-old woman presented to the Emergency Department with a 10-day history of fevers, sore throat, myalgias, and fatigue. In the preceding 2 days, she had noted progressive jaundice with brief intermittent episodes of epigastric pain that were associated with nausea and loose stools. She was a nondrinker with no recent travel history or intravenous drug use. The remainder of her systems review was unremarkable. Her regular medications included an inhaled long-acting beta-agonist/corticosteroid combination, topical steroid cream, and the combined oral contraceptive pill.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Naviglio S
        • Abate MV
        • Chinello M
        • Ventura A
        Splenic infarction in acute infectious mononucleosis.
        J Emerg Med. 2016; 50: e11-e13
        • Ebell MH
        Epstein-Barr virus infectious mononucleosis.
        Am Fam Physician. 2004; 70: 1279-1287
        • Heo DH
        • Baek DY
        • Oh SM
        • Hwang JH
        • Lee CS
        • Hwang JH
        Splenic infarction associated with acute infectious mononucleosis due to Epstein-Barr virus infection.
        J Med Virol. 2017; 89: 332-336
        • Li Y
        • George A
        • Arnaout S
        • Wang JP
        • Abraham GM
        Splenic infarction: an under-recognized complication of infectious mononucleosis?.
        Open Forum Infect Dis. 2018; 5: ofy041
        • Hal SV
        • Senanayake S
        • Hardiman R
        Splenic infarction due to transient antiphospholipid antibodies induced by acute Epstein-Barr virus infection.
        J Clin Virol. 2005; 32: 245-247
        • Won ACM
        • Ethell A
        Spontaneous splenic rupture resulted from infectious mononucleosis.
        Int J Surg Case Rep. 2012; 3: 97-99