Advertisement

Hypokalemia in an End-Stage Renal Disease Patient

      Kidneys play an essential role in K+ homeostasis, but the role of the colon in K+ homeostasis is not well recognized. Increased colonic K+ excretion plays a vital role in regulating plasma K+ level in patients with end-stage renal disease.
      • Sandle GI
      • Gaiger E
      • Tapster S
      • Goodship TH
      Evidence for large intestinal control of potassium homoeostasis in uraemic patients undergoing long-term dialysis.
      We present a case of hypokalemia in a patient with end-stage renal disease with colonic pseudo-obstruction.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Sandle GI
        • Gaiger E
        • Tapster S
        • Goodship TH
        Evidence for large intestinal control of potassium homoeostasis in uraemic patients undergoing long-term dialysis.
        Clin Sci (Lond). 1987; 73: 247-252
        • Hayes Jr., CP
        • McLeod ME
        • Robinson RR
        An extravenal mechanism for the maintenance of potassium balance in severe chronic renal failure.
        Trans Assoc Am Physicians. 1967; 80: 207-216
        • van Dinter Jr, TG
        • Fuerst FC
        • Richardson CT
        • et al.
        Stimulated active potassium secretion in a patient with colonic pseudo-obstruction: a new mechanism of secretory diarrhea.
        Gastroenterology. 2005; 129: 1268-1273
        • Simon M
        • Duong JP
        • Mallet V
        • et al.
        Over-expression of colonic K+ channels associated with severe potassium secretory diarrhoea after haemorrhagic shock.
        Nephrol Dial Transplant. 2008; 23: 3350-3352