ABSTRACT
Background
The aim was to examine the association between habitual consumption of dairy products
and 24-hour ambulatory blood pressure monitoring among older adults with hypertension.
Methods
We conducted an analysis of 715 community-living hypertensive adults age ≥60. Habitual
dairy consumption was assessed with a validated diet history. Blood pressure was recorded
by 24-hour ambulatory blood pressure monitoring; controlled blood pressure was defined
as 24-hour blood pressure <130/80 mm Hg in those under drug treatment. Analyses were adjusted for main confounders,
including diet, hypertension duration, and being on antihypertensive treatment.
Results
After adjustment for confounders, consumers of ≥7 servings/week of whole-fat milk/yogurt
had a diastolic blood pressure 1.40 mm Hg higher (95% confidence interval, 0.01, 2.81) than consumers of <1 serving/week.
By contrast, consumers of ≥7 servings/week of low-fat milk/yogurt had a diastolic
blood pressure 1.74 mm Hg lower (95% confidence interval, –3.26, –0.23) than consumers of <1 serving/week.
Moreover, the odds ratio (95% confidence interval) for controlled blood pressure was
1.83 (1.05-3.08) for those consuming ≥7 servings/week of low-fat milk/yogurt, when
compared with consumers of <1 serving/week. Cheese consumption was not associated
with blood pressure.
Conclusions
Regular consumption of low-fat milk/yogurt was associated with lower 24-hour diastolic
blood pressure and with better blood pressure control among older adults with hypertension.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Dietary therapy in hypertension.N Engl J Med. 2010; 362: 2102-2112
- Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.Hypertension. 2003; 42: 1206-1252
- 2013 ESH/ ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).Eur Heart J. 2013; 34: 2159-2219
- Hypertension Canada's 2016 Canadian Hypertension Education Program guidelines for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension.Can J Cardiol. 2016; 32: 569-588
- Molecular targets of antihypertensive peptides: understanding the mechanisms of action based on the pathophysiology of hypertension.Int J Mol Sci. 2014; 16: 256-283
- Do the lactotripeptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials.Am J Hypertens. 2013; 26: 442-449
- Casein-derived lactotripeptides reduce systolic and diastolic blood pressure in a meta-analysis of randomised clinical trials.Nutrients. 2015; 7: 659-681
- Effect of peptides derived from food proteins on blood pressure: a meta-analysis of randomized controlled trials.Food Nutr Res. 2008; 52: 1641-1645
- Dairy consumption and incidence of hypertension: a dose-response meta-analysis of prospective cohort studies.Hypertension. 2012; 60: 1131-1137
- A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods.J Hum Hypertens. 2012; 26: 3-13
- Dairy consumption, blood pressure, and risk of hypertension: an evidence-based review of recent literature.Curr Cardiovasc Risk Rep. 2011; 5: 287-298
- Longitudinal association of dairy consumption with the changes in blood pressure and the risk of incident hypertension: the Framingham Heart Study.Br J Nutr. 2015; 114: 1887-1899
- Impact of dairy consumption on essential hypertension: a clinical study.Nutr J. 2014; 13: 83
- Effects of low-fat dairy intake on blood pressure, endothelial function, and lipoprotein lipids in subjects with prehypertension or stage 1 hypertension.Vasc Health Risk Manag. 2013; 9: 369-379
- Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.Ann Intern Med. 2001; 135: 1019-1028
- Impact of ambulatory blood pressure monitoring on reclassification of blood pressure prevalence and control.J Clin Hypertens. 2015; 17: 453-461
- Effects of long-term intake of lactotripeptides on cardiovascular risk factors in hypertensive subjects.Eur J Clin Nutr. 2012; 66: 843-849
- Lactotripeptides effect on office and 24-h ambulatory blood pressure, blood pressure stress response, pulse wave velocity and cardiac output in patients with high-normal blood pressure or first-degree hypertension: a randomized double-blind clinical trial.Hypertens Res. 2011; 34: 1035-1040
- Dose-dependent lowering of blood pressure by dairy peptides in mildly hypertensive subjects.Blood Press. 2009; 18: 44-50
- Rationale and methods of the study on nutrition and cardiovascular risk in Spain (ENRICA).Rev Esp Cardiol. 2011; 64: 876-882
- Habitual coffee consumption and 24-h blood pressure control in older adults with hypertension.Clin Nutr. 2016; 35: 1457-1463
- Validity and reproducibility of a Spanish dietary history.PLoS One. 2014; 9: e86074
- Usefulness of heart rate to predict cardiac events in treated patients with high-risk systemic hypertension.Am J Cardiol. 2012; 109: 685-692
- European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring.J Hypertens. 2014; 32: 1359-1366
- Estimation of reproducibility and relative validity of the questions included in the EPIC Physical Activity Questionnaire.Int J Epidemiol. 1997; 26: S181-S189
- A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and women.J Nutr. 2011; 141: 1140-1145
- Dairy consumption and risk of frailty in older adults: a prospective cohort study.J Am Geriatr Soc. 2015; 63: 1852-1860
- Guidelines for management of hypertension: report of the Fourth Working Party of the British Hypertension Society, 2004-BHS IV.J Hum Hypertens. 2004; 18: 139-185
- A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.N Engl J Med. 1997; 336: 1117-1124
- Nutritional renaissance and public health policy.J Nutr Biol. 2017; 3: 124-138
- Effects of non-fat dairy products added to the routine diet on vascular function: a randomized controlled crossover trial.Nutr Metab Cardiovasc Dis. 2015; 25: 364-369
- Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study.BMJ. 2017; 356: j1000
- Systolic pressure is all that matters.Lancet. 2008; 371: 2219-2221
- Effects of dairy protein and fat on the metabolic syndrome and type 2 diabetes.Rev Diabet Stud. 2014; 11: 153-166
- (In:)The special problem of isolated systolic hypertension.in: Black HR Elliott W Hypertension: A Companion to Braunwald ’ s Heart Disease . 2nd ed. Elsevier, New York, NY2013: 126-134
- Low-fat dairy products and blood pressure: follow-up of 2290 older persons at high cardiovascular risk participating in the PREDIMED study.Br J Nutr. 2009; 101: 59-67
- Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association.Hypertension. 2006; 47: 296-308
- Can milk proteins be a useful tool in the management of cardiometabolic health? An updated review of human intervention trials.Proc Nutr Soc. 2016; 75: 328-341
- Comparison of the DASH (Dietary Approaches to Stop Hypertension) diet and a higher-fat DASH diet on blood pressure and lipids and lipoproteins: a randomized controlled trial.Am J Clin Nutr. 2016; 103: 341-347
- Clinical practice guidelines for the management of hypertension in the community. A statement by the American Society of Hypertension and the International Society of Hypertension.J Hypertens. 2014; 32: 3-15
Article info
Publication history
Published online: May 25, 2018
Accepted:
April 25,
2018
Received in revised form:
March 7,
2018
Received:
November 28,
2017
Footnotes
Funding: This work was supported by grants from the State Secretary for R+D of Spain and FEDER/FSE (FIS 12/1166, 13/0288, and 13/02321) and the European Union (FP7 grant agreement 305483-2-the FRAILOMIC Initiative and H2020 grant agreement 635316-ATHLOS Project). The study was also supported by the Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Epidemiología Salud Pública (CIBERESP).
Conflicts of Interest: None.
Authorship: All authors had access to the data and a role in writing this manuscript and have reviewed and approved the submitted version.
Identification
Copyright
© 2018 Published by Elsevier Inc.
