Abstract
Background
The occurrence of a stroke after an acute myocardial infarction is associated with
increased morbidity and mortality rates. However, limited data are available, particularly
from a population-based perspective, about recent trends in the incidence and mortality
rates associated with stroke complicating an acute myocardial infarction.
The purpose of this study was to examine 25-year trends (1986-2011) in the incidence
and in-hospital mortality rates of initial episodes of stroke complicating acute myocardial
infarction.
Methods
The study population consisted of 11,436 adults hospitalized with acute myocardial
infarction at all 11 medical centers in central Massachusetts on a biennial basis
between 1986 and 2011.
Results
In this study cohort, 159 patients (1.4%) experienced an acute first-ever stroke during
hospitalization for acute myocardial infarction. The proportion of patients with acute
myocardial infarction who developed a stroke increased through the 1990s but decreased
slightly thereafter. Compared with patients who did not experience a stroke, those
who experienced a stroke were significantly older, were more likely to be female,
had a previous acute myocardial infarction, had a significant burden of comorbidities,
and were more likely to have died (32.1% vs 10.8%) during their index hospitalization.
Patients who developed a first stroke in the most recent study years (2003-2011) were
more likely to have died during hospitalization than those hospitalized during earlier
study years.
Conclusions
Although the incidence rates of acute stroke complicating acute myocardial infarction
remained relatively stable during the years under study, the in-hospital mortality
rates of those experiencing a stroke have not decreased.
Keywords
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Article info
Publication history
Published online: May 03, 2018
Accepted:
April 6,
2018
Received in revised form:
April 6,
2018
Received:
March 16,
2018
Footnotes
☆Funding: None.
✯✯Conflicts of Interest: None.
✯Authorship: All authors had access to the data and contributed to the writing of this manuscript.
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
