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Clinical Research Study| Volume 131, ISSUE 8, P939-944, August 2018

Reduction in Unnecessary Red Blood Cell Folate Testing by Restricting Computerized Physician Order Entry in the Electronic Health Record

  • Thomas E. MacMillan
    Correspondence
    Requests for reprints should be addressed to: Thomas MacMillan, MD, MSc, FRCPC, Suite 8E-415, 399 Bathurst St, Toronto, ON, M5T 2S8, Canada.
    Affiliations
    Division of General Internal Medicine, University Health Network, Toronto, Ontario, Canada

    Division of General Internal Medicine, Department of Medicine, University of Toronto, Ontario, Canada

    HoPingKong Centre for Excellence in Education and Practice, University Health Network, Toronto, Ontario, Canada
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  • Patrick Gudgeon
    Affiliations
    Division of General Internal Medicine, Department of Medicine, University of Toronto, Ontario, Canada

    Division of General Internal Medicine, Trillium Health Partners, Mississauga, Ontario, Canada
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  • Paul M. Yip
    Affiliations
    Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada

    Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada
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  • Rodrigo B. Cavalcanti
    Affiliations
    Division of General Internal Medicine, University Health Network, Toronto, Ontario, Canada

    Division of General Internal Medicine, Department of Medicine, University of Toronto, Ontario, Canada

    HoPingKong Centre for Excellence in Education and Practice, University Health Network, Toronto, Ontario, Canada
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      Abstract

      Purpose

      The red blood cell (RBC) folate test is a laboratory test with limited clinical utility. Previous attempts to reduce physician ordering of unnecessary laboratory tests, including folate levels, have resulted in only modest success. The objective of this study was to assess the effectiveness and impacts of restricting RBC folate ordering in the electronic health record (EHR).

      Methods

      This was a retrospective observational study that took place from January 2010 to December 2016 at a large academic healthcare network in Toronto, Canada. All inpatients and outpatients who underwent at least 1 RBC folate or vitamin B12 test during the study period were included. Ordering an RBC folate test was restricted to clinicians in gastroenterology and hematology. The option to order the test was removed from other physicians’ computerized order entry screens in the EHR in June 2013.

      Results

      RBC folate testing decreased by 94.4% during the study, from a mean of 493.0 ± 48.0 tests per month prior to intervention to 27.6 ± 10.3 tests per month after intervention (P < .001).

      Conclusions

      Restricting RBC folate ordering in the EHR resulted in a large and sustained reduction in RBC folate testing. Significant cost savings, estimated at more than a quarter of a million Canadian dollars over 3 years, were achieved. There was no significant clinical impact of the intervention on the diagnosis of folate deficiency.

      Keywords

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