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Requests for reprints should be addressed to Eric A. Coomes, MD, University of Toronto, Department of Medicine, Suite RFE 3-805, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada.
A 26-year-old female graduate student with sickle-cell disease presented with fever,
dyspnea, and right shoulder pain. Computed tomography of the chest demonstrated right
middle and lower lobe infiltrates (Figure, A). She was diagnosed with pneumonia, acute chest syndrome, and vaso-occlusive crisis
and prescribed 5 days of amoxicillin-clavulanic acid.
FigureComputed tomography of the chest. (A) Before treatment, with right pulmonary infiltrates. (B) After 1 year of itraconazole, with marked improvement.
Authorship: PB cared for the patient. EAC performed the literature search and wrote the manuscript. Both authors critically revised the manuscript for important intellectual content.
Consent: The patient provided written informed consent for the publication of this manuscript.