Sickle Cough: A Case of Nonresolving Pneumonia

      A 26-year-old female graduate student with sickle-cell disease presented with fever, dyspnea, and right shoulder pain. Computed tomography of the chest demonstrated right middle and lower lobe infiltrates (Figure, A). She was diagnosed with pneumonia, acute chest syndrome, and vaso-occlusive crisis and prescribed 5 days of amoxicillin-clavulanic acid.
      FigureComputed tomography of the chest. (A) Before treatment, with right pulmonary infiltrates. (B) After 1 year of itraconazole, with marked improvement.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Chapman S.W.
        • Dismukes W.E.
        • Proia L.A.
        • et al.
        Clinical practice guidelines for the management of blastomycosis: 2008 update by the infectious diseases society of america.
        Clin Infect Dis. 2008; 46: 1801-1812
        • Harvey A.M.
        • Mody D.R.
        • Amrikachi M.
        Disseminated blastomycosis diagnosed by fine-needle aspiration of the thyroid.
        Diagn Cytopathol. 2011; 39: 446-450
        • Zhang M.X.
        • Klein B.
        Activation, binding, and processing of complement component 3 (C3) by blastomyces dermatitidis.
        Infect Immun. 1997; 65: 1849-1855