Abstract
Inflammatory bowel disease consists of disorders characterized by chronic idiopathic
bowel inflammation. The concept of host–gut–microbiome interaction in the pathogenesis
of various complex immune-mediated chronic diseases, including inflammatory bowel
disease, has recently generated immense interest. Mounting evidence confirms alteration
of intestinal microflora in patients with inflammatory bowel disease. Thus, restoration
of normal gut microbiota has become a focus of basic and clinical research in recent
years. Fecal microbiota transplantation is being explored as one such therapeutic
strategy and has shown encouraging results in the management of patients with inflammatory
bowel disease.
Keywords
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Article info
Publication history
Published online: March 29, 2018
Footnotes
Funding: None.
Conflict of Interest: None.
Authorship: All authors played a significant role in reviewing the literature and drafting the manuscript.
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© 2018 Elsevier Inc. All rights reserved.
