Malignancy is associated with a higher risk of thromboembolic events.
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Clinical practice guidelines recommend injectable antithrombotic drugs for the prevention
of venous thromboembolism in people with malignancies.
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- Kreher S.
- Ochsenreither S.
- Trappe R.U.
- et al.
Prophylaxis and management of venous thromboembolism in patients with myeloproliferative
neoplasms: consensus statement of the Haemostasis Working Party of the German Society
of Hematology and Oncology (DGHO), the Austrian Society of Hematology and Oncology
(OGHO) and Society of Thrombosis and Haemostasis Research (GTH e.V.
Ann Hematol. 2014; 93: 1953-1963
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Guidelines recommend oral anticoagulants for the treatment of thromboembolism in
adults at high risk, although their role in routine prevention of embolic complications
in adults with malignancies is debatable.
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We conducted a rapid literature review following an a priori developed protocol of
all available evidence regarding the benefits and harms of oral anticoagulants for
the prevention of thromboembolism in adults with malignancies undergoing conservative
chemotherapy, immunotherapy, or radiotherapy.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: April 03, 2018
Footnotes
Funding: Elsevier Evidence-Based Medicine Center.
Conflicts of Interest: TAS is employed by Elsevier.
Authorship: All authors had access to the data and played a role in writing this manuscript.
Identification
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© 2018 Elsevier Inc. All rights reserved.
