The diagnosis of acute pancreatitis requires 2 of the following 3 features: 1) abdominal
pain consistent with acute pancreatitis; 2) serum lipase activity (or amylase activity)
at least 3 times greater than the upper limit of normal; and 3) characteristic imaging
findings of acute pancreatitis.
1
Although normal serum amylase levels have been reported in some cases of acute pancreatitis,
2
acute pancreatitis with normal serum lipase has been rarely described in the literature
due to its negative predictive value of between 94% and 100%.
3
Moreover, other pancreatic enzymes have not been mentioned in the previous reports
of acute pancreatitis with normal serum lipase or amylase. Herein, we present a case
of acute pancreatitis with normal serum amylase, lipase, trypsin, elastase-1, and
phospholipase A2.To read this article in full you will need to make a payment
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References
- Classification of acute pancreatitis–2012: revision of the Atlanta classification and definitions by international consensus.Gut. 2013; 62: 102-111
- Acute pancreatitis and normoamylasemia. Not an uncommon combination.Ann Surg. 1989; 210: 614-620
- Normal lipase serum level in acute pancreatitis: a case report.Emerg Med J. 2006; 23: 701-702
- Underestimation of acute pancreatitis: patients with only a small increase in amylase/lipase levels can also have or develop severe acute pancreatitis.Gut. 1999; 44: 542-544
- Acute pancreatitis with normal lipase and amylase: an ED dilemma.Am J Emerg Med. 2016; 34: 2254.e3-2254.e6
- Acute pancreatitis with normal amylase and lipase–an ED dilemma.Am J Emerg Med. 2016; 34 (e5-7): 940
Article info
Publication history
Published online: March 09, 2018
Footnotes
Funding: There has been no significant financial support for this work that could have influenced its outcome.
Conflicts of Interest: There are no conflicts of interest associated with this publication.
Authorship: We obtained informed consent from the patient. The manuscript has been read and approved by all named authors. SK diagnosed the case and wrote the manuscript, and is the article guarantor. KS contributed to and edited the final manuscript.
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
