Advertisement

Koplik's Spots and Measles

  • Giuseppe Famularo
    Correspondence
    Requests for reprints should be addressed to Giuseppe Famularo, MD, PhD, Department of Emergency Medicine, Circonvallazione Gianicolense, 00152, Rome, Italy.
    Affiliations
    Department of Emergency Medicine, San Camillo Hospital, Rome, Italy
    Search for articles by this author
Published:February 21, 2018DOI:https://doi.org/10.1016/j.amjmed.2018.01.030
      Measles, one of the most transmissible diseases, is most contagious before rash manifestation. Search for the pathognomonic Koplik's spots could be critical for the early diagnosis in this prodromal period.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Koplik H.
        A new diagnostic sign of measles.
        Med Rec (NY). 1898; 53: 505-507
        • Moss W.J.
        Measles.
        Lancet. 2017; 390: 2490-2502
        • Corbett E.U.
        The visceral lesions in measles.
        Am J Pathol. 1945; 21: 905-919
        • Rota J.S.
        • Hickman C.J.
        • Sowers S.B.
        • et al.
        Two case studies of modified measles in vaccinated physicians exposed to primary measles cases: high risk of infection but low risk of transmission.
        J Infect Dis. 2011; 204: S559-S563
        • Evans L.M.
        • Grossman M.E.
        • Gregory N.
        Koplik spots and a purpuric eruption associated with parvovirus B19 infection.
        J Am Acad Dermatol. 1992; 27: 466-467
        • Katz S.L.
        • Hinman A.R.
        Summary and conclusions: measles elimination meeting, 16-17 March 2000.
        J Infect Dis. 2004; 189: S43-S47
        • Lo N.C.
        • Hotez P.J.
        Public health and economic consequences of vaccine hesitancy for measles in the United States.
        JAMA Pediatr. 2017; 171: 887-892