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Intracranial Calcification Due to Hypoparathyroidism

Published:January 16, 2018DOI:https://doi.org/10.1016/j.amjmed.2017.12.030
      A 70-year-old Japanese man with a history of idiopathic hypoparathyroidism presented to the Emergency Department of our hospital owing to weakness in his right leg. Although his primary care doctor had prescribed activated vitamin D analogues, his serum calcium level was slightly low at 8.0 mg/dL. Owing to suspicions of stroke, he underwent radiographic imaging of the head. Computed tomography revealed bilateral and symmetrical calcifications in the basal ganglia, cerebellum, and at the gray-white junction in the axial image and the sagittal image (Figure). These findings were consistent with those of long-term hypoparathyroidism. Diffusion-weighted magnetic resonance imaging revealed a high-intensity area in his left deep white matter of the brain, which was consistent with acute cerebral infarction. He received inpatient treatment for acute cerebral infarction and was discharged with functional recovery.
      Figure
      FigureComputed tomography of the head showing bilateral and symmetrical calcifications in basal ganglia in the axial image (A), and in the cerebellum and at the gray-white junction in the sagittal image (B).
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