Abstract
Computer science advances and ultra-fast computing speeds find artificial intelligence
(AI) broadly benefitting modern society—forecasting weather, recognizing faces, detecting
fraud, and deciphering genomics. AI's future role in medical practice remains an unanswered
question. Machines (computers) learn to detect patterns not decipherable using biostatistics
by processing massive datasets (big data) through layered mathematical models (algorithms).
Correcting algorithm mistakes (training) adds to AI predictive model confidence. AI
is being successfully applied for image analysis in radiology, pathology, and dermatology,
with diagnostic speed exceeding, and accuracy paralleling, medical experts. While
diagnostic confidence never reaches 100%, combining machines plus physicians reliably enhances system performance. Cognitive programs are impacting
medical practice by applying natural language processing to read the rapidly expanding
scientific literature and collate years of diverse electronic medical records. In
this and other ways, AI may optimize the care trajectory of chronic disease patients,
suggest precision therapies for complex illnesses, reduce medical errors, and improve
subject enrollment into clinical trials.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- On computable numbers, with an application to the entscheidungsproblem.Proc Lond Math Soc. 1936; Series 2: 230-265
- Deep Learning.The MIT Press, Cambridge MA, London, UK2016: 96-161 (Available at)www.deeplearningbook.orgDate accessed: May 30, 2017
- Deep learning.Nature. 2015; 521: 436-444
- A fast learning algorithm for deep belief nets.Neural Comput. 2006; 18: 1527-1554
- Greedy layer-wise training of deep networks. proc.Adv Neural Inf Process Syst. 2006; 19: 153-160
- The diagnostic performance of computer programs for the interpretation of electrocardiograms.N Engl J Med. 1991; 325: 1767-1773
- Use of an artificial neural network for the diagnosis of myocardial infarction.Ann Intern Med. 1991; 115: 843-848
- Use of a neural network as a predictive instrument for length of stay in the intensive care unit following cardiac surgery.Proc Annu Symp Comput Appl Med Care. 1992; : 666-672
- Deep learning of the tissue-regulated splicing code.Bioinformatics. 2014; 30: i121-i129
- Stegle. Deep learning for computational biology.Mol Syst Biol. 2016; 12 (Available at): 878
- Using deep learning to enhance cancer diagnosis and classification.in: Proceedings of the 30th International Conference on Machine Learning. Vol. 28. JMLR, Atlanta, GA2013
- A deep learning architecture for image representation, visual interpretability and automated basal-cell carcinoma cancer detection.in: Mori K. Sakuma I. Sato Y. Barillot C. Navab N. Medical Image Computing and Computer-Assisted Intervention (MICCAI). Lecture Notes in Computer Science. Vol. 8150. Springer, Berlin, Heidelberg2013: 403-410
- Deep learning for identifying breast cancer.in: Proceedings of the International Society on Biomedical Imaging (ISBI), Quantitative Methods. 2016
- Dermatologist-level classification of skin cancer with deep neural networks.Nature. 2017; 542: 115-119
- Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs.JAMA. 2016; 316: 2402-2410
- Care management processes used less often for depression than for other chronic conditions in us primary care practices.Health Aff (Millwood). 2016; 35: 394-400
- Evaluating the diagnostic utility of applying a machine learning algorithm to diffusion tensor mri measures in individuals with major depressive disorder.Psychiatry Res. 2017; 264 (Available at): 1-9
- Epidemiology of heart failure.Circ Res. 2013; 113: 646-659
- Machine learning in medicine.Circulation. 2015; 132: 1920-1930
- Toward generating domain-specific/personalized problem lists from electronic medical records.(AAAI Fall Symposium, November; Available at)https://www.aaai.org/ocs/index.php/FSS/FSS15/paper/viewFile/11733/11479Date: 2015Date accessed: June 25, 2017
- Predicting healthcare trajectories from medical records: a deep learning approach.J Biomed Inform. 2017; 69 (Available at): 218-229
- The Soul of a New Machine.Little, Brown and Company, Boston, MA1981
- A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systemic analysis for the Global Burden of Disease Study 2010.Lancet. 2012; 380 (Available at): 2224-2260
- Cell phones and cancer risk.(May; Available at)https://www.cancer.gov/about-cancer/causes-prevention/risk/radiation/cell-phones-fact-sheetDate: 2016Date accessed: May 10, 2017
- Technology insertion in the defense industry: a primer.Proc Inst Mech Eng B J Eng Manuf. 2008; 222 (Available at): 1009-1023http://journals.sagepub.comDate accessed: May 15, 2017
Article Info
Publication History
Published online: November 07, 2017
Footnotes
Funding: None.
Conflicts of Interest: DDM: None; EWB: Employed by IBM; the employment relationship did not create direct or indirect financial or scientific conflicts in the preparation of this paper.
Authorship: All authors had access to the data and a role in writing this manuscript.
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.