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Infections of the Nervous System

  • Seth N. Levin
    Affiliations
    Department of Neurology, Massachusetts General Hospital, Boston, Mass

    Department of Neurology, Brigham and Women's Hospital, Boston, Mass

    Harvard Medical School, Boston, Mass
    Search for articles by this author
  • Jennifer L. Lyons
    Correspondence
    Requests for reprints should be addressed to Jennifer L. Lyons, MD, Division of Neurological Infections and Inflammatory Diseases, Department of Neurology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115.
    Affiliations
    Department of Neurology, Brigham and Women's Hospital, Boston, Mass

    Harvard Medical School, Boston, Mass
    Search for articles by this author
Published:September 07, 2017DOI:https://doi.org/10.1016/j.amjmed.2017.08.020

      Abstract

      Microorganisms can affect the entire neuraxis, producing a variety of neurologic complications that frequently entail prolonged hospitalizations and complicated treatment regimens. The spread of pathogens to new regions and the reemergence of opportunistic organisms in immunocompromised patients pose increasing challenges to health care professionals. Because rapid diagnosis and treatment may prevent long-term neurologic sequelae, providers should approach these diseases with a structured, neuroanatomic framework, incorporating a thorough history, examination, laboratory analysis, and neuroimaging in their clinical reasoning and decision-making.

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