Abstract
A patient presented with oxalate-induced acute renal failure that was attributable
to consumption of oxalate-rich fruit and vegetable juices obtained from juicing. We
describe the case and also review the clinical presentation of 65 patients seen at
Mayo Clinic (Rochester, MN) from 1985 through 2010 with renal failure and biopsy-proven
renal calcium oxalate crystals. The cause of renal oxalosis was identified for all
patients: a single cause for 36 patients and at least 2 causes for 29 patients. Three
patients, including our index patient, had presumed diet-induced oxalate nephropathy
in the context of chronic kidney disease. Identification of calcium oxalate crystals
in a kidney biopsy should prompt an evaluation for causes of renal oxalosis, including
a detailed dietary history. Clinicians should be aware that an oxalate-rich diet may
potentially precipitate acute renal failure in patients with chronic kidney disease.
Juicing followed by heavy consumption of oxalate-rich juices appears to be a potential
cause of oxalate nephropathy and acute renal failure.
Keywords
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Article info
Publication history
Published online: July 08, 2013
Footnotes
Funding: None.
Conflict of Interest: None.
Authorship: All authors had access to the data and a role in writing the manuscript.
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© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
