The original description of clubbing of the digits, one of the most important clinical
signs in all of medicine, is attributed to Hippocrates (460 BC).
1
Clubbing continues to fascinate students, clinicians, and researchers, as evidenced
by 165 articles on clubbing published from 1975 to August of 2006.
1
Clubbing is easy to recognize in its advanced stages compared with the early stages,
as evidenced by only moderate agreement among experienced clinicians on the presence
of clubbing.
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References
- Exploring the cause of the most ancient clinical sign of medicine: finger clubbing.Semin Arthritis Rheum. 2007; 36 (Epub 2007 Feb 5): 380-385
- The rational clinical examination.JAMA. 2001; 286: 341-347
- Clubbing: an update on diagnosis, differential diagnosis, pathophysiology, and clinical relevance.J Am Acad Dermatol. 2005; 52: 1020-1028
- A unique eponymous sign of finger clubbing (Schamroth sign) that is named not only after a physician who described it but also after the patient who happened to be the physician himself.Am J Cardiol. 2005; 96: 1614-1615
- What causes clubbing?.Am J Med. 2005; 118: 1350-1351
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© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
