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Pica and food craving in patients with iron-deficiency anemia: A case-control study in France

      Pica, an eating disorder known since antiquity,
      • Parry-Jones B.
      Pagophagia, or compulsive ice consumption a historical perspective.
      is defined as compulsive ingestion of nonfood substances. Its association with iron deficiency is widely recognized;
      • Reynolds R.D.
      • Binder H.J.
      • Miller M.B.
      • Chang W.W.
      • Horan S.
      Pagophagia and iron-deficiency anemia.
      • Rector Jr, W.G.
      Pica its frequency and significance in patients with iron-deficiency anemia due to chronic gastrointestinal blood loss.
      • Rector Jr, W.G.
      • Fortuin N.J.
      • Conley C.L.
      Non-hematologic effects of chronic iron deficiency. A study of patients with polycythemia vera treated solely with venesections.
      a majority of authors postulate that pica is a consequence, rather than a cause, of iron deficiency.
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