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Autoantibodies against carbonic anhydrase II are increased in renal tubular acidosis associated with Sjögren syndrome

      Sjögren syndrome is an autoimmune disorder characterized by chronic inflammation involving the lacrimal and salivary glands, pancreas, and kidneys.
      • Fox R.I.
      • Howell F.V.
      • Bone R.C.
      • Michelson P.
      Primary Sjögren syndrome clinical and immunopathologic features.
      Clinically, renal involvement may manifest as renal tubular acidosis, usually of the distal type,
      • Shioji R.
      • Furuyama T.
      • Onodera S.
      • Saito H.
      • Ito H.
      • Sasaki Y.
      Sjögren’s syndrome and renal tubular acidosis.
      • Talal N.
      Sjögren’s syndrome, lymphoproliferation, and renal tubular acidosis.
      perhaps due to tubulointerstitial nephritis.
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