Functional dyspepsia: the devil in the details

  • Nimish Vakil
    Requests for reprints should be addressed to Nimish Vakil, MD, Aurora Sinai Medical Center, 945 North 12th Street, Room 4040, Milwaukee, Wisconsin 53233, USA
    University of Wisconsin Medical School, Madison, and Marquette University College of Health Sciences, Milwaukee, Wisconsin, USA
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      Dyspepsia (also called uninvestigated dyspepsia) is a syndrome that has been defined as “pain of discomfort in the upper abdomen” by the Rome I consensus group. Functional dyspepsia is defined by a subsequent working group (Rome II) as pain or discomfort in the abdomen in the absence of endoscopic findings that would explain the symptoms (
      • Talley N
      • Stanghellini V
      • Heading R
      • Koch K
      • Malagelada J
      • Tytgat G
      Functional bowel disorders.
      ). An additional requirement is that the symptoms should have lasted 12 weeks in the preceding 12 months. This definition also recognizes the importance of excluding nonerosive reflux disease and suggests that patients with predominant symptoms of heartburn be excluded from the diagnosis of functional dyspepsia.
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