Abstract
Presenting features
A 71-year-old African American woman with a history of rheumatic heart disease was
admitted with worsening dyspnea. Her past medical history was notable for chronic
renal insufficiency and atrial fibrillation. Her medications included diltiazem and
warfarin. Digoxin was added within the past month to improve rate control. In the
2 weeks leading up to admission, she experienced progressive dyspnea on exertion.
Initially, she had difficulty ambulating, but by the day of admission she was breathless
at rest. She also complained of generalized fatigue and a loss of appetite. She denied
any fevers, chills, visual disturbances, nausea, vomiting, palpitations, syncope,
or chest discomfort.
The patient was afebrile on presentation. Her pulse was irregular at a rate of 95
to 105 beats per minute, her blood pressure was 135/80 mm Hg, and her jugular veins
were distended to more than 15 cm above the sternal angle. Laboratory values were
notable for the following: serum creatinine, 3.7 mg/dL; potassium, 3.9 mEq/L; magnesium,
2.7 mg/dL; international normalized ratio, 1.2; and serum digoxin, 2.2 ng/mL. She
was placed on a cardiac monitor, which showed atrial fibrillation with a rapid ventricular
response and frequent premature ventricular depolarizations (Figure 1). Intermittently, she developed a wide-complex tachycardia at a rate of 150 beats
per minute (Figure 2). However, she was asymptomatic and hemodynamically stable during these episodes.
What is the diagnosis?
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Chou’s Electrocardiography in Clinical Practice. 5th ed. W. B. Saunders, Philadelphia, Pennsylvania2001 (509)
- Bidirectional tachycardia.Anesth Analg. 2002; 95: 310-315
- Bidirectional tachycardia: mechanism derived from intracardiac recording and programmed electrical stimulation.Pacing Clin Electrophysiol. 1982; 5: 633-638
- Supraventricular origin of bidirectional tachycardia.Circulation. 1974; 50: 634-638
- His bundle electrogram during bidirectional tachycardia.Br Heart J. 1975; 37: 1198-1201
- Bidirectional tachycardia eliminated with radiofrequency ablation.Pacing Clin Electrophysiol. 2002; 25: 1786-1787
- Infra-his bundle origin of bidirectional tachycardia.Circulation. 1973; 47: 1260-1266
- Digitalis.Circulation. 1999; 99: 1265-1270
- Recognition and management of digitalis toxicity.Am J Cardiol. 1992; 69: 108G-119G
- Diltiazem increases steady state digoxin serum levels in patients with cardiac disease.J Clin Pharmacol. 1987; 27: 967-970
- Sex-based differences in the effect of digoxin for the treatment of heart failure.N Engl J Med. 2002; 347: 1403-1411
Article info
Identification
Copyright
© 2003 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.