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Interstitial cystitis–like urinary symptoms among patients with Sjögren’s syndrome: a population-based study in Finland

      Interstitial cystitis is a chronic, severely debilitating inflammatory condition characterized by urinary frequency, urgency, nocturia, and pain on bladder filling (
      • Hanno P.M.
      • Landis J.R.
      • Matthews-Cook Y.
      • et al.
      The diagnosis of interstitial cystitis revisited: lessons learned from the National Institutes of Health interstitial cystitis database study.
      ). Sjögren’s syndrome is a multiorgan autoimmune exocrinopathy with general mucosal dryness and systemic symptoms. Both syndromes are 10 times more common among women than men. There is anecdotal evidence of an association between these syndromes (
      • Van de Merwe J.
      • Kamerling R.
      • Arendsen E.
      • et al.
      Sjögren’s syndrome in patients with interstitial cystitis.
      ,
      • Haarala M.
      • Alanen A.
      • Hietaranta M.
      • Kiilholma P.
      Lower urinary tract symptoms in patients with Sjögren’s syndrome and systemic lupus erythematosus.
      ). We therefore estimated the prevalence of interstitial cystitis–like symptoms among patients with Sjögren’s syndrome compared with population-based controls.
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