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- CYP1A1 gene polymorphism and risk of epithelial ovarian neoplasm.Gynecol Oncol. 2002; 86: 124-128
- Association of CYP1B1 polymorphisms and breast cancer risk.Cancer Epidemiol Biomarkers Prev. 2002; 11: 489-492
- Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density.J Bone Miner Res. 2005; 20: 232-239
- Estradiol metabolism and malignant disease.Maturitas. 2002; 43: 1-10
- Functional role of estrogen metabolism in target cells: review and perspectives.Carcinogenesis. 1998; 19: 1-27
- P450 enzymes of estrogen metabolism.Pharmacol Ther. 1993; 57: 237-257
- Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells.J Biol Chem. 1984; 259: 4840-4845
- Urinary estrogen metabolites and breast cancer: a case-control study.Cancer Epidemiol Biomarkers Prev. 1997; 6: 505-509
GeneCard for protein-coding CYP1A1 GC15M072798. Web site of the Weizmann Institute of Science. Available at: http://www.genecards.org/cgi-bin/carddisp?CYP1A1. Accessed October 4, 2005.
National Center for Biotechnology Information (NCBI) Entrez SNP. Search for CYP1A1 and CYP1B1. Available at: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp. Accessed September 23, 2005.
- Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.Pharmacogenetics. 2001; 11: 1-6
GeneCard for protein-coding CYP1B1 GC02M038206. Web site of the Weizmann Institute of Science. Available at: http://www.genecards.org/cgi-bin/carddisp?CYP1B1. Accessed October 4, 2005.
- Cell-specific regulation of human CYP1A1 and CYP1B1 genes.Cancer Res. 1997; 57: 1264-1269
- Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status.Carcinogenesis. 1999; 20: 947-955
Single Nucleotide Polymorphism database: dbSNP search page. National Center for Biotechnology Information Web site. Available at: http://www.ncbi.nlm.nih.gov/SNP/. Accessed September 23, 2005.
- Design, survey sampling and recruitment methods of SWAN: a multicenter, multiethnic, community-based cohort study of women and the menopausal transition.in: Lobo R.A. Kelsey J. Marcus R. Menopause: Biology and Pathobiology. Academic Press, San Diego, CA2000: 175-188
- Characterizing variation in sex steroid hormone pathway genes in women of 4 races/ethnicities: the Study of Women’s Health Across the Nation (SWAN).Am J Med. 2006; 119: S3-S15
- Assessing menstrual cycles with urinary hormone assays.Am J Physiol Endocrinol Metab. 2003; 284: E521-E530
- Monoclonal antibody-based enzyme immunoassay for simultaneous quantitation of 2- and 16α-hydroxyestrone in urine.Steroids. 1994; 59: 648-655
- Epidemiology Standardization Project (American Thoracic Society).Am Rev Respir Dis. 1978; 188: 1-120
- Polymorphisms of estrogen synthesizing and metabolizing genes and breast cancer risk in Japanese women.Biomed Pharmacother. 2003; 57: 471-481
- Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations.Xenobiotica. 2000; 30: 285-295
- Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples.J Hum Genet. 2003; 48: 654-658
- Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women.Cancer Epidemiol Biomarkers Prev. 2004; 13: 94-101
The Study of Women’s Health Across the Nation (SWAN) and the SWAN Repository were supported by grants from the National Institutes of Health (NIH), Department of Health and Human Services, through the National Institute on Aging, the National Institute of Nursing Research, and the NIH Office of Research on Women’s Health (Grant Nos. AG017719, NR004061, AG012505, AG012535, AG012531, AG012539, AG012546, AG012553, AG012554, and AG012495). The Sex Steroid Hormone Genetics Protocol was supported by the SWAN Repository.
This report is based on DNA and urine samples from the SWAN Repository. Scientists interested in developing studies based on this resource, can find a description of the SWAN Core Repository and DNA Repository and information on obtaining access to the resources can be found at www.swanrepository.org.