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Research Article| Volume 92, ISSUE 2, P121-124, February 1992

Absolutely relative: How research results are summarized can affect treatment decisions

  • Lachlan Forrow
    Correspondence
    Requests for reprints should be addressed to Lachlan Forrow, M.D., Division of General Medicine and Primary Care, Beth Israel Hospital, 330 Brookline Avenue, Boston, Massachusetts 02215.
    Affiliations
    Division of General Medicine and Primary Care, Department of Medicine, Harvard Medical School, Beth Israel Hospital, the Charles A. Dana Research Institute, and the Harvard Thorndike Laboratory Boston, Massachusetts, USA

    Program in Ethics and the Professions, Harvard University, Boston, Massachusetts, USA
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  • William C. Taylor
    Affiliations
    Division of General Medicine and Primary Care, Department of Medicine, Harvard Medical School, Beth Israel Hospital, the Charles A. Dana Research Institute, and the Harvard Thorndike Laboratory Boston, Massachusetts, USA
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  • Robert M. Arnold
    Affiliations
    Center for Medical Ethics, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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      Abstract

      purpose: To determine whether alternative methods of presenting a contrast between the same two quantities in descriptions of research results could lead to different treatment decisions by physicians.
      subjects and methods: We conducted a survey of practicing physicians and of faculty and fellows in training programs in clinical epidemiology and social science research methods. Each questionnaire presented results from a published study of either hypertension or hypercholesterolemia in two different ways: once as the relative change in the outcome rate and once as the absolute change in the outcome rate. We asked respondents to read each summary and indicate how the information contained in the summary would influence decisions about treatment.
      results: Of the 235 physicians who completed the questionnaire, 108 (46%) gave different responses to the same results presented in different ways. Of these, 97 (89.8%) indicated a stronger inclination to treat patients after reading of the relative change in the outcome rate (p <0.0001).
      conclusion: The manner of presentation of results can influence physicians' judgments about the treatment of patients.

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