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Abstract
The clinical features in eight patients with neurologic abnormalities typical of Lyme
disease and elevated titers of antibody to the spirochete, Borrelia burgdorferi, its
causative agent, are described. None of the patients had the diagnostic skin lesion,
erythema chronicum migrans. Lyme arthritis, the other clinical marker for the disease,
developed subsequently in only three. The neurologic abnormalities included aseptic
meningitis, encephalitis, cranial neuritis, motor and sensory radiculitis, and myelitis
in various combinations. The occurrence of severe encephalitis resulting in dementia
in two of these patients and irreversible myelopathy in one enlarges the known spectrum
of neurologic abnormalities due to infection with B. burgdorferi. Lyme disease can
present with neurologic abnormalities without diagnostic extraneural features, can
be suspected on clinical and epidemiologic grounds, and can be diagnosed serologically.
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Article info
Publication history
Accepted:
May 28,
1985
Identification
Copyright
© 1986 Published by Elsevier Inc.
