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Mucosal eosinophilic gastroenteritis with systemic involvement

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      Abstract

      The unusual features in a 46 year old white woman with mucosal eosinophilic gastroenteritis are described. In addition to involvement of the gastrointestinal tract, she had eosinophilic splenitis and hepatitis. She responded to corticosteroid therapy, but not to an elimination diet or to cromolyn sodium therapy. The possible role of various factors chemotactic for eosinophilia in the patient are reviewed, and the place of the disorder among the hypereosinophilic syndromes is discussed.
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      References

        • Finch SC
        Granulocytosis.
        (chap 76)in: William JW Bentler E Erslev AJ Wayne RR Hematology. McGraw-Hill Book Co, New York1972
        • Zucher FD
        Eosinophil function and disorders.
        Adv Intern Med. 1975; 19: 1
        • Hardy RW
        • Anderson RE
        The hypereosinophilic syndromes.
        Ann Intern Med. 1968; 68: 1220
        • Benvenisti DS
        • Ultmann JE
        Eosinophilic leukemia. Report of five cases and review of literature.
        Ann Intern Med. 1969; 71: 731
        • Pierce LE
        • Hasseinian AH
        • Constantine AB
        Disseminated eosinophilic collagen disease.
        Blood. 1967; 29: 540
        • Klein NC
        • Hargrove RL
        • Sleisenger MH
        • et al.
        Eosinophilic gastroenteritis.
        Medicine (Baltimore). 1970; 49: 299
        • Edelman MJ
        • March TL
        Eosinophilic gastroenteritis.
        Am J Roentgenol Radium Ther Nucl Med. 1964; 91: 773
        • Rebhum J
        Systemic eosinophilic infiltrative disease.
        Ann Allergy. 1974; 32: 86
        • Lachman PJ
        • Kay AB
        • Thompson RA
        The chemotactic activity for neutrophils and eosinophilic leukocytes of the trimolecular complex of the 5th, 6th, and 7th components of human complement prepared in free solution by the ‘reactive lysis’ procedure.
        Immunology. 1970; 19: 895
        • Wasserman SI
        • Goetzl EJ
        • Austen FK
        Preformed eosinophil chemotactic factor of anaphylaxis.
        J Immunol. 1974; 112: 351
        • Wasserman SE
        • Goetzel EJ
        • Ellman L
        • et al.
        Tumor-associated eosinophilic factor.
        N Engl J Med. 1974; 290: 420
      1. Wasserman SI: Personal communication, 1974.

        • Leinbach GE
        • Rubin CE
        Eosinophilic gastroenteritis. A simple reaction to food allergens?.
        Gastroenterology. 1970; 59: 874
        • Burhenne HJ
        • Carbone JV
        Eosinophilic (allergic) gastroenteritis.
        Am J Roentgenol Radium Ther Nucl Med. 1966; 96: 332
        • Domonkos AN
        Reticuloses.
        (chap 19)in: Domonkos AN Andrews' Diseases of the Skin. W. B. Saunders, Philadelphia1971
        • Jacobson LB
        Diffuse eosinophilic gastroenteritis. An adult form of allergic gastroenteropathy.
        Am J Gastroenterol Radium Ther Nucl Med. 1970; 54: 580
        • Speirs RS
        Advances in the knowledge of the eosinophil in relation to antibody formation.
        Ann NY Acad Sci. 1958; 73: 283
        • Kelenyl G
        • Nemeth A
        • Istran L
        • et al.
        Effect of corticosteroids on eosinophil leukocytes in hypereosinophilic syndromes.
        Acta Haematol. 1973; 49: 235
        • Orr TSC
        • Cox JSG
        Disodium cromoglycate, an inhibitor of mast cell degranulation and histamine release induced by phospholipase.
        A. Nature (Lond). 1969; 223: 197
        • Easton JG
        Effect of cromolyn sodium on the peripheral eosinophilia of asthmatic children.
        Ann Allergy. 1973; 31: 134
        • Kingsley PJ
        Oral sodium cromoglycate in gastrointestinal allergy.
        Lancet. 1974; 2: 1011