This paper is only available as a PDF. To read, Please Download here.
Abstract
In 1963, 10,000 men aged 40 years and over were examined; those without myocardial
infarction or angina pectoris were followed for the next 5 years (1963–1968) to see
what factors (variables) found in 1963 were associated with the development of angina
pectoris by 1968.
The average annual adjusted incidence for angina pectoris was 7.2/1,000; the incidence
was highest (11.2) in those bom in Southeastern Europe and lowest (3.8) in those born
in the Middle East. The incidence rose with age until age 59 and then plateaued off.
The variables found significantly associated (p <0.01) with the development of angina
pectoris were as follows: Clinical—blood pressure (systolic and diastolic), intermittent claudication, diabetes mellitus,
nonspecific T waves in the electrocardiogram, serum cholesterol (total and in beta-lipoprotein).
Psychosocial—anxiety and severe problems as seen by the subject in whatever area of his life situation,
as well as, or because of, moving from one country to another. Blood group—A1BJka−. In addition, overweight, peptic ulcer and lack of physical activity are probably
of importance.
A knowledge of the factors associated with the development of angina pectoris is a
“sine qua non” for the clinician who is interested in preventing the condition or
aiding the patient who already has it.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The American Journal of MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Myocardial infarction among 10,000 adult males over a 5 year period. I. Prevalence, incidence and mortality experience.J Chron Dis. 1973; 26: 68
- An epidemiologic investigation of hypertension and ischemic heart disease within a defined segment of the adult male population of Israel.Israel J Med Sci. 1968; 4: 177
- The diagnosis of ischemic heart pain and intermittent claudication in field studies.WHO, Geneva1961 (WHO/H and IHD/Meth)
- The HIP study of incidence and prognosis of coronary heart disease: criteria for diagnosis.J Chron Dis. 1963; 16: 1293
- Some practical problems of observer variation in a large survey in cardiology—current topics and progress.Israel J Med Sci. 1970; 6 (suppl): 100
- WHO Technical Report Series 168. 1959; (Geneva)
- Blood groups, myocardial infarction and angina pectoris among 10,000 adult males.N Engl J Med. 1971; 285: 1348
- Variability of angina: some implications for epidemiology.Br J Prev Soc Med. 1968; 22: 12
- The Framingham Study.in: Kannel WB Gordon T An Epidemiological Investigation of Cardiovascular Disease. U.S. Government Printing Office, Washington, D.C1970 (Sect 26)
- The differential effect of serum cholesterol, blood pressure and weight on the incidence of myocardial infarction and angina pectoris.J Chron Dis. 1971; 23: 631
- Epidemiology of ischemic heart disease.Am J Med. 1969; 46: 674
- The interrelationship of serum cholesterol, hypertension, body weight, and risk of coronary disease. Results of the first ten years' follow-up in the Los Angeles heart study.J Chron Dis. 1964; 17: 933
- The epidemiology of ischemic heart disease.Trans Soc Occup Med. 1968; 18: 127
- Coronary heart disease in the Western collaborative group study.J Chron Dis. 1970; 23: 173
- Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 1
- Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 2
- Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 82
- Hyperglycemia and hypertriglyceridemia among persons with coonary heart disease.Ann Intern Med. 1967; 67: 34
- Premature coronary artery disease and the preclinical diabetic state.Am J Med. 1965; 67: 481
- Hereditary factors and angina pectoris.Arch Environ Health. 1967; 14: 397
- The filtration concept of atherosclerosis and serum lipids in the diagnosis of atherosclerosis.(chap 6)in: Sandler M Bourne GH Atherosclerosis and Its Origin. Academic Press, New York and London1963
- The epidemiology of coronary heart disease; a review.J Chroh Dis. 1965; 18: 735
- Cigarette smoking and coronary heart disease: combined experience of the Albany and Framingham studies.N Engl J Med. 1962; 226: 796
- The HIP study of incidence and prognosis of coronary heart disease.J Chron Dis. 1965; 18: 527
- Role of emotional stress preceding coronary occlusion.Am J Cardiol. 1959; 5: 590
- Determinants of angina pectoris.Psychosomatic Med. 1967; 29: 621
- Psychosomatic Diagnosis.Paul B. Hoeber, New York1943
- Psychoanalytic observations in cardiac disorders.Am Heart J. 1936; 11: 10
- Emotional correlates of angina pectoris.J Am Geriatrics Soc. 1968; 16: 845
- Psychosocial factors in coronary heart disease.Industrial Med. 1970; 39: 383
- Overt behaviour pattern in coronary disease.JAMA. 1960; 173: 1320
- A prospective study of the relationship between personality and coronary heart disease.J Chron Dis. 1964; 17: 265
- Psychologic and social precursors of coronary disease.N Engl J Med. 1971; 284: 244
- Psychologic and social precursors of coronary disease.N Engl J Med. 1971; 284: 307
- Levine S Scotch NA Physical Illness in Response to Stress in Social Stress. Aldine Co, Chicago1970
- Het Acute Myocardinfarct Een Psychosomatische Studie.De Erven F. Bohn, Haarlem1965
Article info
Publication history
Accepted:
May 25,
1973
Footnotes
☆This study was supported by P.L. 480 Counterpart Funds, Research Agreement No. 375106 and was carried out by the Ischemic Heart Disease Project for the Hadassah Medical Organization and Ministry of Health, Jerusalem, Israel, and the National Heart and Lung Institute, Bethesda, Maryland, U.S.A.
Identification
Copyright
© 1973 Published by Elsevier Inc.
