Advertisement

Angina pectoris among 10,000 men

5 Year incidence and univariate analysis
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      In 1963, 10,000 men aged 40 years and over were examined; those without myocardial infarction or angina pectoris were followed for the next 5 years (1963–1968) to see what factors (variables) found in 1963 were associated with the development of angina pectoris by 1968.
      The average annual adjusted incidence for angina pectoris was 7.2/1,000; the incidence was highest (11.2) in those bom in Southeastern Europe and lowest (3.8) in those born in the Middle East. The incidence rose with age until age 59 and then plateaued off.
      The variables found significantly associated (p <0.01) with the development of angina pectoris were as follows: Clinical—blood pressure (systolic and diastolic), intermittent claudication, diabetes mellitus, nonspecific T waves in the electrocardiogram, serum cholesterol (total and in beta-lipoprotein). Psychosocial—anxiety and severe problems as seen by the subject in whatever area of his life situation, as well as, or because of, moving from one country to another. Blood group—A1BJka−. In addition, overweight, peptic ulcer and lack of physical activity are probably of importance.
      A knowledge of the factors associated with the development of angina pectoris is a “sine qua non” for the clinician who is interested in preventing the condition or aiding the patient who already has it.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Medalie JH
        • Kahn HA
        • Neufeld HN
        • Goldbourt U
        • Riss E
        • Perlstein T
        • Oron D
        Myocardial infarction among 10,000 adult males over a 5 year period. I. Prevalence, incidence and mortality experience.
        J Chron Dis. 1973; 26: 68
        • Groen JJ
        • Medalie JH
        • Neufeld HN
        • Riss E
        • Bachrach CA
        • Mount FW
        • Smith H
        An epidemiologic investigation of hypertension and ischemic heart disease within a defined segment of the adult male population of Israel.
        Israel J Med Sci. 1968; 4: 177
        • Rose GA
        The diagnosis of ischemic heart pain and intermittent claudication in field studies.
        WHO, Geneva1961 (WHO/H and IHD/Meth)
        • Frank CW
        • Weinblatt E
        • Shapiro S
        • Seiden GE
        • Sager RV
        The HIP study of incidence and prognosis of coronary heart disease: criteria for diagnosis.
        J Chron Dis. 1963; 16: 1293
        • Medalie JH
        • Riss E
        • Neufeld HN
        • Kahn HA
        • Perlstein T
        • Balogh M
        • Baruch D
        • Sive P
        • Goldbourt U
        Some practical problems of observer variation in a large survey in cardiology—current topics and progress.
        Israel J Med Sci. 1970; 6 (suppl): 100
      1. WHO Technical Report Series 168. 1959; (Geneva)
        • Medalie JH
        • Levene C
        • Papier C
        • Goldbourt U
        • Dreyfuss F
        • Oron D
        • Neufeld H
        • Riss E
        Blood groups, myocardial infarction and angina pectoris among 10,000 adult males.
        N Engl J Med. 1971; 285: 1348
        • Rose G
        Variability of angina: some implications for epidemiology.
        Br J Prev Soc Med. 1968; 22: 12
        • Shurtleff D
        The Framingham Study.
        in: Kannel WB Gordon T An Epidemiological Investigation of Cardiovascular Disease. U.S. Government Printing Office, Washington, D.C1970 (Sect 26)
        • Chapman JM
        • Coulson AH
        • Clark VA
        • Borun ER
        The differential effect of serum cholesterol, blood pressure and weight on the incidence of myocardial infarction and angina pectoris.
        J Chron Dis. 1971; 23: 631
        • Morris JN
        • Gardner MJ
        Epidemiology of ischemic heart disease.
        Am J Med. 1969; 46: 674
        • Chapman JM
        • Massey FJ
        The interrelationship of serum cholesterol, hypertension, body weight, and risk of coronary disease. Results of the first ten years' follow-up in the Los Angeles heart study.
        J Chron Dis. 1964; 17: 933
        • Meade TW
        The epidemiology of ischemic heart disease.
        Trans Soc Occup Med. 1968; 18: 127
        • Rosenman RH
        • Friedman M
        • Straus R
        • Jenkins CD
        • Zyzanski SJ
        • Wurm M
        Coronary heart disease in the Western collaborative group study.
        J Chron Dis. 1970; 23: 173
      2. Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 1
      3. Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 2
      4. Brest AN Coronary Heart Disease: Cardiovascular Clinics. F. A. Davis Co, Philadelphia1969: 82
        • Ostrander LD
        • Neff BJ
        • Block WD
        • Francis Jr, T
        • Epstein FH
        Hyperglycemia and hypertriglyceridemia among persons with coonary heart disease.
        Ann Intern Med. 1967; 67: 34
        • Herman MV
        • Gorlin R
        Premature coronary artery disease and the preclinical diabetic state.
        Am J Med. 1965; 67: 481
        • Cederlof R
        • Friberg L
        • Jonsson E
        Hereditary factors and angina pectoris.
        Arch Environ Health. 1967; 14: 397
        • Gofman JW
        • Young W
        The filtration concept of atherosclerosis and serum lipids in the diagnosis of atherosclerosis.
        (chap 6)in: Sandler M Bourne GH Atherosclerosis and Its Origin. Academic Press, New York and London1963
        • Epstein FH
        The epidemiology of coronary heart disease; a review.
        J Chroh Dis. 1965; 18: 735
        • Doyle JT
        • Dewher TR
        • Kannel WB
        • Merlin AS
        • Kahn HA
        Cigarette smoking and coronary heart disease: combined experience of the Albany and Framingham studies.
        N Engl J Med. 1962; 226: 796
        • Shapiro S
        • Weinblatt E
        • Frank CW
        • Sager RV
        The HIP study of incidence and prognosis of coronary heart disease.
        J Chron Dis. 1965; 18: 527
        • Dreyfuss F
        Role of emotional stress preceding coronary occlusion.
        Am J Cardiol. 1959; 5: 590
        • Bakker CB
        • Levenson RM
        Determinants of angina pectoris.
        Psychosomatic Med. 1967; 29: 621
        • Dunbar F
        Psychosomatic Diagnosis.
        Paul B. Hoeber, New York1943
        • Menninger KA
        • Menninger WC
        Psychoanalytic observations in cardiac disorders.
        Am Heart J. 1936; 11: 10
        • Wendkos MH
        • Wolff K
        Emotional correlates of angina pectoris.
        J Am Geriatrics Soc. 1968; 16: 845
        • French Jr, JRP
        • Caplan RD
        Psychosocial factors in coronary heart disease.
        Industrial Med. 1970; 39: 383
        • Friedman M
        • Rosenman RH
        Overt behaviour pattern in coronary disease.
        JAMA. 1960; 173: 1320
        • Ostfeld AM
        • Lebovits BZ
        • Shekelle RB
        • Paul O
        A prospective study of the relationship between personality and coronary heart disease.
        J Chron Dis. 1964; 17: 265
        • Jenkins CD
        Psychologic and social precursors of coronary disease.
        N Engl J Med. 1971; 284: 244
        • Jenkins CD
        Psychologic and social precursors of coronary disease.
        N Engl J Med. 1971; 284: 307
        • Cassel J
        Levine S Scotch NA Physical Illness in Response to Stress in Social Stress. Aldine Co, Chicago1970
        • Groen JJ
        • Var der Valk JM
        • Treurniet N
        • Van Heljningen Hk
        • Pelser HE
        • Wilde GJS
        Het Acute Myocardinfarct Een Psychosomatische Studie.
        De Erven F. Bohn, Haarlem1965