The concurrence of osteitis deformans and acoustic neurinoma

  • Larry K. Page
    Requests for reprints should be addressed to Dr. Larry K. Page.
    Boston, Massachusetts USA
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  • Author Footnotes
    ∗ Present address: Department of Neurological Surgery, University of Miami School of Medicine, P.O. Box 875, Biscayne Annex, Miami, Florida 33152.
    1 From the Department of Surgery (Division of Neurosurgery) Peter Bent Brigham Hospital, 721 Huntington Avenue, Boston, Massachusetts 02115.
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      A fifty-four year old woman with Paget's disease of the skull had progressive deafness and tinnitus for eight years prior to the diagnosis and operative removal of a large acoustic neurinoma. This rare diagnostic challenge should be met with the knowledge that osteitis deformans commonly produces bilateral sensorineural and conductive hearing loss, causing no diminution of corneal reflex or asymmetry of facial expression. Acoustic neurinoma produces unilateral deafness of only sensorineural type, but routinely involves the fifth and seventh cranial nerves and causes an increase in cerebrospinal fluid protein as the tumor expands intracranially.
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