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Composition and structure of urinary stone

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      Abstract

      A knowledge of the composition of urinary stone is important because urolithiasis is a recurrent disease in many people and preventive measures must be based on such information. In stones of mixed composition knowledge of the structure, as well as of the composition, may be important in delineating pathogenesis. Analysis by the crystallographic technics of polarization microscopy and x-ray diffraction photography permit accurate identification of all parts of the stone, including a very small nucleus, and are preferable to chemical methods. The crystalline compounds in urinary calculi and the details and significance of calculus structure are described.
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      References

        • Meyer J.
        Über die Ausfällung von Sedimenten und die Bildung von Konkrementen in den Harnwegen.
        Ztschr. klin. Med. 1929; 111: 613
        • Higgins C.C.
        Renal Lithiasis.
        in: Charles C Thomas, Springfield, Ill1943: 53
        • Nakano H.
        Beiträge zur Kenntnis der in den Harnsteinen enthaltenen Substanzen.
        J. Biochem. 1922; 2: 437
        • Hammarsten G.
        On calcium oxalate and its solubility in the presence of inorganic salts with special reference to the occurrence of oxaluria.
        Compt. rend. trav. lab. Carlsberg, série chim. 1929; 17: 11
        • Hammarsten G.
        Eine experimentelle Studie über Calciumoxalat als Steinbildner in den Harnwegen.
        in: Lunds Universitets Årsskrift, N.F. Avd. 2. Bd 32. C. W. K. Gleerup, Lund1937 (nr 12)
        • Saupe E.
        Röntgendiagramme von menschlichen Körpergeweben und Konkrementen.
        Fortschr. Geb. Röntgenstrahlen. 1931; 44: 204
        • Tovberg Jensen A.
        • Thygesen J.E.
        Über die Phosphatkonkremente der Harnwege.
        Ztschr. Urol. 1938; 32: 659
        • Tovberg Jensen A.
        On concrements from the urinary tract. II.
        Acta chir. scandinav. 1940; 84: 217
        • Tovberg Jensen A.
        On concrements from the urinary tract. III.
        Acta chir. scandinav. 1941; 85: 473
        • Prien E.L.
        The use of polarized light in the analysis of calculi and the study of crystals in tissue. A preliminary report on the method employed.
        J. Urol. 1941; 45: 765
        • Frondel C.
        • Prien E.L.
        Carbonate apatite and hydroxyl apatite in urinary calculi.
        Science. 1942; 95: 431
        • Prien E.L.
        • Frondel C.
        Studies in urolithiasis. I. The composition of urinary calculi.
        J. Urol. 1947; 57: 949
        • Prien E.L.
        Studies in urolithiasis. II. Relationships between pathogenesis, structure and composition of calculi.
        J. Urol. 1949; 61: 821
        • Prien E.L.
        Studies in urolithiasis. III. Physicochemical principles in stone formation and prevention.
        J. Urol. 1955; 73: 627
        • Prien E.L.
        Crystallographic analysis of urinary calculi. A 23 year survey study.
        J. Urol. 1963; 89: 917
        • Lagergren C.
        Biophysical investigations of urinary calculi.
        Acta Radiol. 1956; 133 (supp.): 1
        • Herring L.C.
        Observations in the analysis of ten thousand urinary calculi.
        J. Urol. 1962; 88: 545
        • Boyce W.H.
        • King Jr., J.S.
        Crystal matrix interrelations in calculi.
        J. Urol. 1959; 81: 351
        • Finlayson B.
        • Vermeulen C.W.
        • Stewart E.J.
        Stone matrix and mucoprotein from urine.
        J. Urol. 1961; 86: 355
        • Frondel C.
        Whitlockite. A new calcium phosphate, Ca3(PO4)2.
        Am. Mineral. 1941; 26: 145
        • Parsons J.
        Magnesium dibasic phosphate identified as crystalline component of a urinary calculus.
        J. Urol. 1956; 76: 228
        • Lonsdale K.
        • Sutor D.J.
        Newberyite in ancient and modern urinary calculi. Identification and space group.
        Science. 1966; 154: 1353
        • Ringertz H.
        Optical and crystallographic data of uric acid and its dihydrate.
        Acta Cryst. 1965; 19: 286
        • Shirley R.
        Uric acid dihydrate. Crystallography and identification.
        Science. 1966; 153: 1512
        • Lonsdale K.
        • Mason P.
        Uric acid, uric acid dihydrate, and urates in urinary calculi, ancient and modern.
        Science. 1966; 152: 1511
        • Gershoff S.N.
        • Prien E.L.
        • Chandrapanond A.
        Urinary stones in Thailand.
        J. Urol. 1963; 90: 285
      1. Hammarsten, G. Personal communication, 1964.

      2. Pyrah, L. Personal communication, 1964.

        • Herman J.R.
        • Goldberg A.S.
        New type of urinary calculus caused by antacid therapy.
        J.A.M.A. 1960; 174: 1206
      3. M.D. Medical Newsmagazine. 1961; 5: 128
        • Prout W.
        An Inquiry Into the Nature and Treatment of Diabetes, Calculus and Other Affections of the Urinary Organs.
        Baldwin, Craddock and Joy, London1925
      4. Catalog of the Calculi and Other Animal Concretions Contained in the Museum of the Royal College of Surgeons in London. 1842; (London)
        • Nakano H.
        Atlas der Harnsteine. F. Deuticke, Leipzig and Vienna1925
        • Randall A.
        The etiology of primary renal calculus.
        in: VII Congress of the International Society of Urology. I. Reports. 1939: 186 (New York)
        • Rosenow Jr., E.C.
        Renal calculi, a study of papillary calcification.
        J. Urol. 1940; 44: 9
        • Vermooten V.
        The incidence and significance of the deposition of calcium plaques in the renal papilla as observed in the Caucasian and Bantu (Negro) population in South Africa.
        J. Urol. 1941; 46: 193
      5. Anderson, C. K. Personal communication, 1967.

        • Henneman P.H.
        • Wallach S.
        • Dempsey E.F.
        The metabolic defect responsible for uric acid stone formation.
        J. Clin. Invest. 1962; 41: 537
        • Yü T.-F.
        • Gutman A.B.
        Uric acid nephrolithiasis in gout.
        Ann. Int. Med. 1967; 67: 1133
        • Joly J.S.
        The etiology and preventive treatment of urinary lithiasis.
        in: Report of Congress of the Seventh International Society of Urology. 1938: 124 (pt. 1)
        • Joly J.S.
        The etiology and preventive treatment of urinary lithiasis.
        in: Report of Congress of the Seventh International Society of Urology. 1939: 120 (pt. 1)
        • Thomas J.M.R.
        Vesical calculus in Norfolk.
        Brit. J. Urol. 1949; 21: 20
        • Eckstein H.S.
        Endemic urinary lithiasis in Turkish children.
        Arch. Dis. Childhood. 1961; 36: 137