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Systemic mast cell disease in a patient with unusual gastrointestinal and pulmonary abnormalities

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      Abstract

      A forty-one year old man had urticaria pigmentosa since 1954. Systemic mast cell disease became apparent in 1963 and progressed to involve bone, spleen and lymph nodes. There was roentgenographic evidence of widespread involvement of the gastrointestinal tract and a large retroperitoneal mass thought to represent enlarged lymph nodes. Diffuse nodular interstitial infiltrates were apparent on chest roentgenograms and most likely represent pulmonary mastocytosis.
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