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Diabetic anhidrosis

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      Abstract

      A symptom-complex characterized by intolerance to heat was encountered in five diabetic patients. The patients became extremely uncomfortable in warm weather and complained of hyperhidrosis of the head, neck and upper torso. In contrast, the skin of the lower extremities and lower body was dry. Also present in these patients was evidence of diabetic retinopathy and neuropathy. Diabetic anhidrosis is thus another manifestation of diabetic neuropathy in which the peripheral sympathetic nerves are damaged in the course of diabetes.
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      References

        • Bernard C.
        Leçons sur le Diabète et la Glycogénese Animale.
        Baillière, Paris1877
        • Pavy P.W.
        Introductory address to the discussion on the clinical aspects of glycosuria.
        Lancet. 1885; 2: 1085
        • Pryce T.D.
        On diabetic neuritis, with a clinical and pathological description of three cases of diabetic pseudotabes.
        Brain. 1893; 16: 416
        • Fleming R.A.
        Notes of two cases of peripheral neuritis, with comparative results of experimental nerve degeneration and changes in nerve cells.
        Brain. 1897; 20: 56
        • Rundles R.W.
        Diabetic neuropathy. General review with report of 125 cases.
        Medicine. 1945; 24: 111
        • Swarts J.M.
        • Stine L.A.
        Visceral neuropathy complicating diabetes mellitus.
        Am. J. Med. 1948; 5: 610
        • Treusch J.V.
        Diabetic neuritis: a tentative working classification.
        in: Proc. Staff Meet., Mayo Clin.20. 1945: 393 (Discussion by Sprague, R. G. and Woltman, H. W.)
        • Broch O.J.
        • Klövstad O.
        Polyneuritis in diabetes mellitus.
        Acta med. scandinav. 1947; 127: 514
        • Auché B.
        Des altérations des nerfs péripheriques chez les diabètiques.
        Arch. méd. epèr. et anat. path. 1890; 2: 635
        • Odel H.M.
        • Roth G.M.
        • Keating F.R.
        Autonomic neuropathy simulating the effects of sympathectomy as a complication of diabetes mellitus.
        Diabetes. 1955; 4: 92
        • Woltman H.W.
        • Wilder R.M.
        Diabetes mellitus: pathologic changes in the spinal cord and peripheral nerves.
        Arch. Int. Med. 1929; 44: 576
        • Jordan W.R.
        Neuritic manifestations in diabetes mellitus.
        Arch. Int. Med. 1936; 57: 307
        • Rundles R.W.
        Diabetic neuropathy.
        Bull. New York Acad. Med. 1950; 26: 598
        • Bermer Jr., J.
        Orthostatic hypotension in diabetes mellitus.
        Acta med. scandinav. 1952; 143: 336
        • Minor V.
        Eines neues Verfahren zu der klinischen Untersuchungen der Schweissabsonderung.
        Deutsche Ztschr. Nervenh. 1927; 101: 302
        • Brown G.E.
        • Adson A.W.
        Physiologic effects of thoracic and lumbar sympathetic ganglionectomy or section of trunk.
        Arch. Neurol. & Psychiat. 1929; 22: 322
        • Guttmann L.
        Topographic studies of disturbances of sweat secretion after complete lesions of peripheral nerves.
        J. Neurol. & Psychiat. 1940; 3: 197
        • Lowenberg R.I.
        • Hutchin P.
        Surgical implications of sweating.
        J.A.M.A. 1963; 184: 558
        • List C.F.
        • Peet M.M.
        Sweat secretion in man.
        Arch. Neurol. & Psychiat. 1938; 39: 1228
        • Hyndman O.R.
        • Wolkin J.
        Sweat mechanism in man: study of distribution of sweat fibers from sympathetic ganglia, spinal roots, spinal cord and common carotid artery.
        Arch. Neurol. & Psychiat. 1941; 45: 446
        • Shumacker Jr., H.B.
        Sympathetic denervation of the feet and legs occurring spontaneously or as a result of disease; a preliminary report.
        Bull. Johns Hopkins Hosp. 1942; 71: 1
        • Wilkins R.W.
        • Kolb L.C.
        Vasomotor disturbances in peripheral neuritis.
        Am. J. M. Sc. 1941; 202: 216
        • Wolkin J.
        • Goodman J.I.
        • Kelley W.E.
        Failure of the sweat mechanism in the desert.
        J.A.M.A. 1944; 124: 478
        • Head H.
        • Riddoch G.
        The automatic bladder, excessive sweating and some other reflex conditions, in gross injuries of the spinal cord.
        Brain. 1917; 40: 188
        • Goodman J.I.
        • et al.
        The Diabetic Neuropathies.
        Charles C Thomas, Springfield, Ill1953