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Brisket disease

II. Clinical features and hemodynamic observations in altitude-dependent right heart failure of cattle
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      Abstract

      In cattle grazing during the summer months at altitudes between 8,000 and 12,000 feet (2,500 to 3,700 meters) in Utah and Colorado severe congestive heart failure develops.
      The disease is apparently the consequence of severe pulmonary hypertension which develops in this species in response to moderate altitudes. This form of chronic mountain sickness has many similarities to pulmonary hypertensive heart disease in man. It differs from Monge's disease in certain significant aspects.
      It is assumed that the peculiar structure of the pulmonary vascular bed in this species causes an excessive vasoconstrictive response at a reduction in partial pressure of oxygen which is still easily tolerated by man.
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