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Pseudoxanthoma elasticum

A systemic disorder
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      Abstract

      The characteristics of pseudoxanthoma elasticum, and of its association with angioid streaks (Grönblad-Strandberg syndrome) are described. Evidence has accumulated that the disease is of systemic nature and may be associated with ambylopia, hemorrhage from gastrointestinal and other sites, coronary and peripheral vascular insufficiency, cerebral insufficiency and perhaps certain endocrinopathies.
      Three relevant case reports are recorded, one resembling lupus erythematosus, another associated with Marfan's syndrome, and a third giving a history of repeated and severe gastrointestinal bleeding.
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