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Clinical study| Volume 14, ISSUE 2, P160-167, February 1953

The control of hypertension with 1-hydrazinophthalazine (apresoline)

DOI:https://doi.org/10.1016/0002-9343(53)90015-1
The control of hypertension with 1-hydrazinophthalazine (apresoline)
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      Abstract

      • 1.
        1. The results of treatment of sixty-five hypertensive patients with 1-hydrazinophthalazine are presented.
      • 2.
        2. Patients with essential hypertension or malignant hypertension responded favorably.
      • 3.
        3. Patients with hypertension of the “renal” type showed an insignificant response.
      • 4.
        4. Postsympathectomy patients with persistent hypertension had variable responses and judgment as to the value of the drug must be delayed until more cases are studied.
      • 5.
        5. Undesirable side effects caused ten patients to discontinue the drug.
      • 6.
        6. The pharmacology of 1-hydrazinophthalazine is discussed.
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      Article info

      Footnotes

      ☆Supported in part by the Middle Tennessee Heart Association and Ciba Pharmaceutical Products, Inc.

      Identification

      DOI: https://doi.org/10.1016/0002-9343(53)90015-1

      Copyright

      © 1953 Published by Elsevier Inc.

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