The American Journal of Medicine
Volume 123, Issue 9 , Pages 863.e7-863.e13 , September 2010

Agreement between Erythrocyte Sedimentation Rate and C-Reactive Protein in Hospital Practice

  • Isabelle Colombet, MD, PhD

      Affiliations

    • Hospital Informatics and Public Health, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, France
    • Medical School, Université Paris Descartes, Faculté de médecine, France
    • ,
  • Jacques Pouchot, MD

      Affiliations

    • Department of Internal Medicine, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, France
    • Medical School, Université Paris Descartes, Faculté de médecine, France
    • ,
  • Vladimir Kronz, MD

      Affiliations

    • Department of Internal Medicine, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, France
    • ,
  • Xavier Hanras, MSc

      Affiliations

    • Medical School, Université Paris Descartes, Faculté de médecine, France
    • ,
  • Loïc Capron, MD, PhD

      Affiliations

    • Department of Internal Medicine, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, France
    • Medical School, Université Paris Descartes, Faculté de médecine, France
    • ,
  • Pierre Durieux, MD

      Affiliations

    • Hospital Informatics and Public Health, Hôpital Européen Georges Pompidou, Assistance Publique–Hôpitaux de Paris, France
    • Medical School, Université Paris Descartes, Faculté de médecine, France
    • ,
  • Benjamin Wyplosz, MD, PhD

      Affiliations

    • Assistance Publique–Hôpitaux de Paris, Hôpital Paul Brousse, Infectious and Tropical Diseases Unit, France
    • Corresponding Author InformationReprint requests should be addressed to: Benjamin Wyplosz, MD, PhD, Unité de Maladies Infectieuses et Tropicales, Hôpital Paul Brousse, 12-14 avenue Paul Vaillant-Couturier, 94804 Villejuif, France

References 

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  2. Guidelines on selection of laboratory tests for monitoring the acute phase response (International Committee for Standardization in Haematology (expert panel on blood rheology)). J Clin Pathol. 1988;41:1203–1212
  3. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest. 2003;111:1805–1812
  4. Jurado RL. Why shouldn't we determine the erythrocyte sedimentation rate?. Clin Infect Dis. 2001;33:548–549
  5. Sox HC, Liang MH. The erythrocyte sedimentation rate (Guidelines for rational use). Ann Intern Med. 1986;104:515–523
  6. Miller A, Green M, Robinson D. Simple rule for calculating normal erythrocyte sedimentation rate. Br J Med. 1983;286:266
  7. Bottiger LE, Svedberg CA. Normal erythrocyte sedimentation rate and age. Br Med J. 1967;2:85–87
  8. Tsouderos Y, Chretien J, Ryckewaert A. Erythrocyte sedimentation rate in a population of 47,205 adults (Variation with age). Rev Rhum Mal Osteoartic. 1982;49:583–587
  9. Griffiths RA, Good WR, Watson NP, et al. Normal erythrocyte sedimentation rate in the elderly. Br Med J (Clin Res Ed). 1984;289:724–725
  10. Shearn MA, Kang IY. Effect of age and sex on the erythrocyte sedimentation rate. J Rheumatol. 1986;13:297–298
  11. Keshet R, Boursi B, Maoz R, et al. Diagnostic and prognostic significance of serum C-reactive protein levels in patients admitted to the department of medicine. Am J Med Sci. 2009;337:248–255
  12. Chalmers JD, Singanayagam A, Hill AT. C-reactive protein is an independent predictor of severity in community-acquired pneumonia. Am J Med. 2008;121:219–225
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  14. Caswell M, Stuart J. Assessment of Diesse Ves-matic automated system for measuring erythrocyte sedimentation rate. J Clin Pathol. 1991;44:946–949
  15. Penchas S, Stern Z, Bar-Or D. Heparin and the ESR. Arch Intern Med. 1978;138:1864–1865
  16. Kameneva MV, Antaki JF, Watach MJ, et al. Heparin effect on red blood cell aggregation. Biorheology. 1994;31:297–304
  17. Zezos P, Papaioannou G, Nikolaidis N, et al. Low-molecular-weight heparin (enoxaparin) as adjuvant therapy in the treatment of active ulcerative colitis: a randomized, controlled, comparative study. Aliment Pharmacol Ther. 2006;23:1443–1453
  18. Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas. 1960;20:37–46
  19. Cicchetti DV, Feinstein AR. High agreement but low kappa: II (Resolving the paradoxes). J Clin Epidemiol. 1990;43:551–558
  20. Kenny RA, Saunders AP, Coll A, et al. A comparison of the erythrocyte sedimentation rate and serum C-reactive protein concentration in elderly patients. Age Ageing. 1985;14:15–20
  21. Katz PR, Gutman SI, Richman G, et al. Erythrocyte sedimentation rate and C-reactive protein compared in the elderly. Clin Chem. 1989;35:466–468
  22. Dinant GJ, de Kock CA, van Wersch JW. Diagnostic value of C-reactive protein measurement does not justify replacement of the erythrocyte sedimentation rate in daily general practice. Eur J Clin Invest. 1995;25:353–359
  23. Buess T, Ludwig C. [Diagnostic value of C-reactive protein in comparison with erythrocyte sedimentation as routine admission diagnostic test]. Schweiz Med Wochenschr. 1995;125:120–124
  24. Hansson LO, Carlsson I, Hansson E, et al. Measurement of C-reactive protein and the erythrocyte sedimentation rate in general practice. Scand J Prim Health Care. 1995;13:39–45
  25. Looney S. Statistical methods for assessing biomarkers. In:  Looney S editors. Biostatistical Methods. Volume 184:Totowa, NJ: Humana Press; 2002;p. 81–111

 Funding: None.

 Conflict of Interest: The authors state that they have no conflict of interest regarding the content of the article.

 Authorship: All authors had access to the data and played a role in writing this manuscript.

PII: S0002-9343(10)00393-1

doi: 10.1016/j.amjmed.2010.04.021

The American Journal of Medicine
Volume 123, Issue 9 , Pages 863.e7-863.e13 , September 2010

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