The American Journal of Medicine
Volume 123, Issue 8 , Pages 735-740 , August 2010

Venous Compression for Prevention of Postthrombotic Syndrome: A Meta-analysis

  • Muzammil H. Musani, MD

      Affiliations

    • Department of Internal Medicine, St. Joseph Mercy Oakland, Pontiac, Mich
  • ,
  • Fadi Matta, MD

      Affiliations

    • Departments of Internal Medicine and Research and Advanced Studies Program, College of Osteopathic Medicine, Michigan State University, East Lansing
  • ,
  • Abdo Y. Yaekoub, MD

      Affiliations

    • Department of Internal Medicine, St. Mary Mercy, Livonia, Mich
  • ,
  • Jane Liang, MSc

      Affiliations

    • Department of Medicine, University of Calgary, Alberta, Canada
  • ,
  • Russell D. Hull, MBBS, MSc

      Affiliations

    • Department of Medicine, University of Calgary, Alberta, Canada
  • ,
  • Paul D. Stein, MD

      Affiliations

    • Departments of Internal Medicine and Research and Advanced Studies Program, College of Osteopathic Medicine, Michigan State University, East Lansing
    • Corresponding Author InformationRequests for reprints should be addressed to Paul D. Stein, MD, Department of Internal Medicine, Michigan State University, College of Osteopathic Medicine, MSU Venous Thromboembolism Research Unit, 44405 Woodward Ave., Pontiac, MI 48341-5023

  • Image Result

    Proportional effects of venous compression on prevention of mild-to-moderate postthrombotic syndrome. Overall relative risk with venous compression was 0.52 (P <.001). Black squares=point estimates (w

    Proportional effects of venous compression on prevention of mild-to-moderate postthrombotic syndrome. Overall relative risk with venous compression was 0.52 (P <.001). Black squares=point estimates (with area proportional to number of events) and horizontal lines=95% confidence interval (CI) for observed effects in different subgroups; diamonds=point estimate and 95% CI for overall effects, with proportional reductions indicated alongside; long vertical line=hazard ratio of 1.0 (ie, no effect of treatment), and shorter vertical line=observed overall effect.

  • Image Result
    Proportional effects of venous compression on prevention of severe postthrombotic syndrome. Overall relative risk with venous compression was 0.38 (P <.001). Black squares=point estimates (with area p

    Proportional effects of venous compression on prevention of severe postthrombotic syndrome. Overall relative risk with venous compression was 0.38 (P <.001). Black squares=point estimates (with area proportional to number of events) and horizontal lines=95% confidence interval (CI) for observed effects in different subgroups; diamonds=point estimate and 95% CI for overall effects, with proportional reductions indicated alongside; long vertical line=hazard ratio of 1.0 (ie, no effect of treatment), and shorter vertical line=observed overall effect.

  • Image Result
    Proportional effects of venous compression on prevention of mild to-severe postthrombotic syndrome. Overall relative risk with venous compression was 0.54 (P <.001). Black squares=point estimates (wit

    Proportional effects of venous compression on prevention of mild to-severe postthrombotic syndrome. Overall relative risk with venous compression was 0.54 (P <.001). Black squares=point estimates (with area proportional to number of events) and horizontal lines=95% confidence interval (CI) for observed effects in different subgroups; diamonds=point estimate and 95% CI for overall effects, with proportional reductions indicated alongside; long vertical line=hazard ratio of 1.0 (ie, no effect of treatment), and shorter vertical line=observed overall effect.

 Funding: None.

 Conflict of Interest: None of the authors have any financial or other potential conflicts of interest relative to the data in this manuscript.

 Authorship: All authors had access to the data and a role in writing the manuscript.

PII: S0002-9343(10)00352-9

doi: 10.1016/j.amjmed.2010.01.027

The American Journal of Medicine
Volume 123, Issue 8 , Pages 735-740 , August 2010